RL3A_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL3A_SCHPO
• UniProt AC: P40372
• Protein Name: 60S ribosomal protein L3-A
• Gene Name: rpl301
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 388
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MSHCKFEQPRHGSLGFLPRKRASRQRGKVKAFPKDDASKPVHLTAFLGYKAGMTHIVRDLDRPGSKMHKREILEAVTVIETPPMVVVGVVGYVETPRGLRSLTTVWAEHLSEEVKRRFYKNWFKSKKKAFTKYAKKYAESTQSINRELERIKKYCSVVRVLAHTQIRKTPLAQKKAHLMEIQVNGGSVADKVEWAREHFEKTVDIKSTFEQNEMIDVIGVTRGKGNEGTTARWGTKRLPRKTHRGLRKVACIGAWHPANVQWTVARAGNAGYMHRTQLNSKIYRIGAGDDAKNASTDFDATEKRITPMGGFVRYGVVENDFVMLNGATPGPVKRVLTLRKSLLTHTSRKALEPVSLKWIDTASKFGHGRFQTPAEAKQFLGTLKKDVA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	FEQPRHGSLGFLPRK CCCCCCCCCCCCCCH	21.13	28889911
38	Phosphorylation	AFPKDDASKPVHLTA ECCCCCCCCCEEEHE	44.48	25720772
65	Phosphorylation	RDLDRPGSKMHKREI CCCCCCCCHHCHHHH	29.50	28889911
137	Phosphorylation	FTKYAKKYAESTQSI HHHHHHHHHHHHHHH	18.20	25720772
140	Phosphorylation	YAKKYAESTQSINRE HHHHHHHHHHHHHHH	24.47	28889911
141	Phosphorylation	AKKYAESTQSINREL HHHHHHHHHHHHHHH	20.17	29996109
143	Phosphorylation	KYAESTQSINRELER HHHHHHHHHHHHHHH	23.17	28889911
156	Phosphorylation	ERIKKYCSVVRVLAH HHHHHHHHHHHHHHC	22.13	28889911
187	Phosphorylation	EIQVNGGSVADKVEW EEEECCCCHHHHHHH	18.61	24763107
207	Phosphorylation	EKTVDIKSTFEQNEM HHHCCHHHHHCCCCE	38.37	28889911
295	Phosphorylation	GDDAKNASTDFDATE CCCCCCCCCCCCCCC	37.59	28889911
341	Phosphorylation	RVLTLRKSLLTHTSR HHHHHHHHHHHHCCC	23.37	28889911
355	Phosphorylation	RKALEPVSLKWIDTA CHHCCCCCCEEEECC	34.64	28889911
372	Phosphorylation	FGHGRFQTPAEAKQF HCCCCCCCHHHHHHH	23.04	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL3A_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL3A_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL3A_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YGNB_SCHPO	nap2	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13; SER-65; SER-140;SER-143; SER-207; SER-295; SER-355 AND THR-372, AND MASS SPECTROMETRY.
PubMed: 18257517