RL35A_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL35A_MOUSE
• UniProt AC: O55142
• Protein Name: 60S ribosomal protein L35a
• Gene Name: Rpl35a
• Organism: Mus musculus (Mouse).
• Sequence Length: 110
• Protein Description: Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site..
• Protein Sequence: MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGRLWCKA ------CCCCHHHHH	32.40	22324799
8	Acetylation	MSGRLWCKAIFAGYK CCCCHHHHHHHHHHH	32.70	22826441
14	Phosphorylation	CKAIFAGYKRGLRNQ HHHHHHHHHHHHCCC	8.29	-
15	Acetylation	KAIFAGYKRGLRNQR HHHHHHHHHHHCCCC	38.79	22826441
15	Ubiquitination	KAIFAGYKRGLRNQR HHHHHHHHHHHCCCC	38.79	-
15	Succinylation	KAIFAGYKRGLRNQR HHHHHHHHHHHCCCC	38.79	23954790
29	Acetylation	REHTALLKIEGVYAR CCCEEEEEEEEEECC	39.29	22826441
34	Phosphorylation	LLKIEGVYARDETEF EEEEEEEECCCCCEE	13.53	-
45	Succinylation	ETEFYLGKRCAYVYK CCEEEECCEEEEEEE	41.53	23954790
45	Ubiquitination	ETEFYLGKRCAYVYK CCEEEECCEEEEEEE	41.53	-
49	Phosphorylation	YLGKRCAYVYKAKNN EECCEEEEEEECCCC	14.13	29514104
54	Ubiquitination	CAYVYKAKNNTVTPG EEEEEECCCCEECCC	46.72	-
59	Phosphorylation	KAKNNTVTPGGKPNK ECCCCEECCCCCCCC	17.74	22802335
63	Succinylation	NTVTPGGKPNKTRVI CEECCCCCCCCEEEE	51.86	-
63	Succinylation	NTVTPGGKPNKTRVI CEECCCCCCCCEEEE	51.86	23806337
63	Acetylation	NTVTPGGKPNKTRVI CEECCCCCCCCEEEE	51.86	23806337
63	Ubiquitination	NTVTPGGKPNKTRVI CEECCCCCCCCEEEE	51.86	-
73	Acetylation	KTRVIWGKVTRAHGN CEEEEEEEEEECCCC	25.99	22826441
90	Phosphorylation	MVRAKFRSNLPAKAI CCCHHHHCCCCHHHH	45.94	19854140
95	Acetylation	FRSNLPAKAIGHRIR HHCCCCHHHHCCEEE	38.30	22826441
95	Ubiquitination	FRSNLPAKAIGHRIR HHCCCCHHHHCCEEE	38.30	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL35A_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL35A_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL35A_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RL35A_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.