RL22_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL22_MOUSE
• UniProt AC: P67984
• Protein Name: 60S ribosomal protein L22
• Gene Name: Rpl22
• Organism: Mus musculus (Mouse).
• Sequence Length: 128
• Protein Sequence: MAPVKKLVAKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Acetylation	---MAPVKKLVAKGG ---CCCHHHHHCCCC	39.05	166003
6	Acetylation	--MAPVKKLVAKGGK --CCCHHHHHCCCCC	48.72	166007
10	Acetylation	PVKKLVAKGGKKKKQ CHHHHHCCCCCCCCE	61.80	166011
22	Phosphorylation	KKQVLKFTLDCTHPV CCEEEEEEECCCCCC	21.79	26239621
25	S-palmitoylation	VLKFTLDCTHPVEDG EEEEEECCCCCCCCC	4.18	28526873
25	S-nitrosylation	VLKFTLDCTHPVEDG EEEEEECCCCCCCCC	4.18	21278135
25	Glutathionylation	VLKFTLDCTHPVEDG EEEEEECCCCCCCCC	4.18	24333276
25	S-nitrosocysteine	VLKFTLDCTHPVEDG EEEEEECCCCCCCCC	4.18	-
26	Phosphorylation	LKFTLDCTHPVEDGI EEEEECCCCCCCCCC	28.96	26239621
52	Ubiquitination	ERIKVNGKAGNLGGG HHHHHCCCCCCCCCC	48.17	22790023
62	Phosphorylation	NLGGGVVTIERSKSK CCCCCEEEEECCCCE	18.08	22817900
66	Phosphorylation	GVVTIERSKSKITVT CEEEEECCCCEEEEE	28.61	22324799
68	Phosphorylation	VTIERSKSKITVTSE EEEECCCCEEEEEEE	30.45	29514104
69	Acetylation	TIERSKSKITVTSEV EEECCCCEEEEEEEC	46.24	23806337
69	Succinylation	TIERSKSKITVTSEV EEECCCCEEEEEEEC	46.24	23806337
69	Malonylation	TIERSKSKITVTSEV EEECCCCEEEEEEEC	46.24	26320211
69	Succinylation	TIERSKSKITVTSEV EEECCCCEEEEEEEC	46.24	-
74	Phosphorylation	KSKITVTSEVPFSKR CCEEEEEEECCCCHH	32.06	29514104
80	Succinylation	TSEVPFSKRYLKYLT EEECCCCHHHHHHHH	45.50	23806337
80	Acetylation	TSEVPFSKRYLKYLT EEECCCCHHHHHHHH	45.50	23806337
84	Acetylation	PFSKRYLKYLTKKYL CCCHHHHHHHHHHHH	29.31	22826441
106	Phosphorylation	WLRVVANSKESYELR HHHHHHCCCCEEEEE	28.23	29514104
107	Ubiquitination	LRVVANSKESYELRY HHHHHCCCCEEEEEE	50.95	-
107	Acetylation	LRVVANSKESYELRY HHHHHCCCCEEEEEE	50.95	22826441
107	Malonylation	LRVVANSKESYELRY HHHHHCCCCEEEEEE	50.95	26320211
109	Phosphorylation	VVANSKESYELRYFQ HHHCCCCEEEEEEEE	27.87	23737553
110	Phosphorylation	VANSKESYELRYFQI HHCCCCEEEEEEEEE	21.78	23737553

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL22_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL22_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL22_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RL22_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.