RL14_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL14_MOUSE
• UniProt AC: Q9CR57
• Protein Name: 60S ribosomal protein L14
• Gene Name: Rpl14
• Organism: Mus musculus (Mouse).
• Sequence Length: 217
• Protein Description: Component of the large ribosomal subunit..
• Protein Sequence: MVFRRYVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAAILKASPKKAAVAKAAIAAAAAAAAAKAKVPAKKATGPGKKAAGQKAPAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MVFRRYVEVGRVA --CCCCEEEEECCEE	9.19	29514104
14	Phosphorylation	VEVGRVAYISFGPHA EEECCEEEEEECCCC	8.34	29514104
42	S-nitrosocysteine	RALVDGPCTRVRRQA CCCCCCCCHHHHHHH	4.67	-
42	S-palmitoylation	RALVDGPCTRVRRQA CCCCCCCCHHHHHHH	4.67	28526873
42	S-nitrosylation	RALVDGPCTRVRRQA CCCCCCCCHHHHHHH	4.67	20925432
42	Glutathionylation	RALVDGPCTRVRRQA CCCCCCCCHHHHHHH	4.67	24333276
53	Acetylation	RRQAMPFKCMQLTDF HHHHCCCHHHHHHHH	23.95	22826441
54	S-nitrosocysteine	RQAMPFKCMQLTDFI HHHCCCHHHHHHHHH	1.83	-
54	S-palmitoylation	RQAMPFKCMQLTDFI HHHCCCHHHHHHHHH	1.83	28526873
54	S-nitrosylation	RQAMPFKCMQLTDFI HHHCCCHHHHHHHHH	1.83	20925432
54	Glutathionylation	RQAMPFKCMQLTDFI HHHCCCHHHHHHHHH	1.83	24333276
63	Ubiquitination	QLTDFILKFPHSARQ HHHHHHHHCCHHHHH	52.62	-
79	Acetylation	YVRKAWEKADINTKW HHHHHHHHCCCCHHH	40.43	23864654
79	Ubiquitination	YVRKAWEKADINTKW HHHHHHHHCCCCHHH	40.43	27667366
79	Malonylation	YVRKAWEKADINTKW HHHHHHHHCCCCHHH	40.43	26320211
79	Succinylation	YVRKAWEKADINTKW HHHHHHHHCCCCHHH	40.43	23806337
85	Succinylation	EKADINTKWAATRWA HHCCCCHHHHHHHHH	30.28	23806337
85	Acetylation	EKADINTKWAATRWA HHCCCCHHHHHHHHH	30.28	23806337
85	Succinylation	EKADINTKWAATRWA HHCCCCHHHHHHHHH	30.28	-
85	Ubiquitination	EKADINTKWAATRWA HHCCCCHHHHHHHHH	30.28	-
103	Ubiquitination	DARERKAKMTDFDRF CHHHHHHCCCCHHHH	45.42	27667366
124	Ubiquitination	KMRNRIIKTEVKKLQ HHHHHHHHHHHHHHH	35.94	27667366
137	Ubiquitination	LQRAAILKASPKKAA HHHHHHHHCCHHHHH	40.48	27667366
137	Malonylation	LQRAAILKASPKKAA HHHHHHHHCCHHHHH	40.48	26320211
139	Phosphorylation	RAAILKASPKKAAVA HHHHHHCCHHHHHHH	35.35	18388127
147	Ubiquitination	PKKAAVAKAAIAAAA HHHHHHHHHHHHHHH	31.58	27667366
160	Acetylation	AAAAAAAKAKVPAKK HHHHHHHHCCCCHHH	43.97	23806337
160	Succinylation	AAAAAAAKAKVPAKK HHHHHHHHCCCCHHH	43.97	23806337
160	Ubiquitination	AAAAAAAKAKVPAKK HHHHHHHHCCCCHHH	43.97	27667366
160	Malonylation	AAAAAAAKAKVPAKK HHHHHHHHCCCCHHH	43.97	26320211
179	Malonylation	GKKAAGQKAPAQKAA CHHHCCCCCHHHHHC	56.26	32601280
184	Malonylation	GQKAPAQKAAGQKAA CCCCHHHHHCCCCCC	42.16	26320211
189	Malonylation	AQKAAGQKAAPPAKG HHHHCCCCCCCCCCC	45.67	26320211
189	Succinylation	AQKAAGQKAAPPAKG HHHHCCCCCCCCCCC	45.67	23806337
189	Ubiquitination	AQKAAGQKAAPPAKG HHHHCCCCCCCCCCC	45.67	27667366
189	Acetylation	AQKAAGQKAAPPAKG HHHHCCCCCCCCCCC	45.67	23806337
195	Malonylation	QKAAPPAKGQKGQKT CCCCCCCCCCCCCCC	68.59	32601280
202	Phosphorylation	KGQKGQKTPAQKAPA CCCCCCCCCCCCCCC	18.90	25266776
206	Succinylation	GQKTPAQKAPAPKAA CCCCCCCCCCCCHHC	59.45	23806337
206	Malonylation	GQKTPAQKAPAPKAA CCCCCCCCCCCCHHC	59.45	26320211
206	Ubiquitination	GQKTPAQKAPAPKAA CCCCCCCCCCCCHHC	59.45	27667366
206	Acetylation	GQKTPAQKAPAPKAA CCCCCCCCCCCCHHC	59.45	23806337
206	Succinylation	GQKTPAQKAPAPKAA CCCCCCCCCCCCHHC	59.45	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL14_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL14_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL14_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RL14_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.