RL10_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL10_MOUSE
• UniProt AC: Q6ZWV3
• Protein Name: 60S ribosomal protein L10 {ECO:0000305}
• Gene Name: Rpl10 {ECO:0000312|MGI:MGI:105943}
• Organism: Mus musculus (Mouse).
• Sequence Length: 214
• Protein Description: Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development..
• Protein Sequence: MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Ubiquitination	CRGVPDAKIRIFDLG CCCCCCCEEEEEECC	39.64	22790023
32	Citrullination	GVPDAKIRIFDLGRK CCCCCEEEEEECCCC	23.86	-
32	Citrullination	GVPDAKIRIFDLGRK CCCCCEEEEEECCCC	23.86	24463520
42	Ubiquitination	DLGRKKAKVDEFPLC ECCCCCCCCCCCCCC	60.13	22790023
49	S-nitrosocysteine	KVDEFPLCGHMVSDE CCCCCCCCCCCCCHH	3.42	-
49	S-nitrosylation	KVDEFPLCGHMVSDE CCCCCCCCCCCCCHH	3.42	21278135
49	S-palmitoylation	KVDEFPLCGHMVSDE CCCCCCCCCCCCCHH	3.42	28526873
54	Phosphorylation	PLCGHMVSDEYEQLS CCCCCCCCHHHHHHC	19.70	17242355
57	Phosphorylation	GHMVSDEYEQLSSEA CCCCCHHHHHHCHHH	17.61	25159016
74	Ubiquitination	AARICANKYMVKSCG HHHHHHHHHHHHHCC	19.05	22790023
80	S-nitrosylation	NKYMVKSCGKDGFHI HHHHHHHCCCCCEEE	6.95	21278135
80	S-nitrosocysteine	NKYMVKSCGKDGFHI HHHHHHHCCCCCEEE	6.95	-
101	Ubiquitination	FHVIRINKMLSCAGA CEEEEHHCCHHHCCH	38.56	22790023
104	Phosphorylation	IRINKMLSCAGADRL EEHHCCHHHCCHHHH	9.83	22817900
105	S-palmitoylation	RINKMLSCAGADRLQ EHHCCHHHCCHHHHH	3.40	28526873
105	S-nitrosocysteine	RINKMLSCAGADRLQ EHHCCHHHCCHHHHH	3.40	-
105	S-nitrosylation	RINKMLSCAGADRLQ EHHCCHHHCCHHHHH	3.40	22178444
121	Ubiquitination	GMRGAFGKPQGTVAR CCCCCCCCCCCCEEE	27.93	22790023
125	Phosphorylation	AFGKPQGTVARVHIG CCCCCCCCEEEEEHH	13.02	29514104
137	Phosphorylation	HIGQVIMSIRTKLQN EHHHHHHHHHHHHCC	9.59	29514104
145	Ubiquitination	IRTKLQNKEHVIEAL HHHHHCCHHHHHHHH	35.91	22790023
188	Acetylation	FEDMVAEKRLIPDGC HHHHHHHHCCCCCCC	42.65	23236377
188	Ubiquitination	FEDMVAEKRLIPDGC HHHHHHHHCCCCCCC	42.65	22790023
195	S-palmitoylation	KRLIPDGCGVKYIPN HCCCCCCCCCEECCC	8.05	28526873
198	Acetylation	IPDGCGVKYIPNRGP CCCCCCCEECCCCCC	23.81	22826441
198	Ubiquitination	IPDGCGVKYIPNRGP CCCCCCCEECCCCCC	23.81	22790023
199	Phosphorylation	PDGCGVKYIPNRGPL CCCCCCEECCCCCCH	21.14	29514104
208	Ubiquitination	PNRGPLDKWRALHS- CCCCCHHHHHHHCC-	46.38	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL10_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL10_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL10_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RL10_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.