dbPTM

RKP_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RKP_ARATH
UniProt AC	Q9SIZ8
Protein Name	E3 ubiquitin-protein ligase RKP
Gene Name	RKP
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1280
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of KRP1 and KRP2..
Protein Sequence	MAEDSLRVGMISSGLAVLLNGEDAKENSSKARIVPHFDYSGHRPLERTIEFIFGLAEKSVGPLDGQVDSSLIRAVIKNQFSKLHGDLDVSVSQREGISVVHHGVGPPIVGLEEFSICGDIRIVKPPLVLESLALFSSARANACIWKGKWMYEVALETSGIQQLGWATLACPFTDQKGVGDADDSYAFDGRRVSKWNKEAEPYGQSWVAGDVIGCCIDLNCDEIYFYRNGVSLGAAFTGIRKLGPGFGYYPAISLSQGERCELNFGAYPFKYPVDGFQPLQEAPTRFSFATELLRCFSRLLDRPDRSLADTLSRLRRFASVEELFCPVSSAICDEFFYILEQDPLLAEYLGRGAFLSFLLETFRTQAPHDSSSLDKVLDVFLEFPQSHLIFEHVVNALACGCKTATLILTECPYSGPYPYLALACHLFKREELMVQWWRSLHFEFLFEGFLSCRSSNKHDLQHLMPVVWWPGSSEDISYESSMGFTISALSEAINKIEEKQRNLCLLVIQFIPPVSPPQLPGSAFRGFLQNLLLKNRGADRTLAPSGVTRNSVLVSLFSVILHFLSEGFAMLKSSEAVHHNVGFLHRGGQQKFPLSLFLKNDPHRADITRLGGLFSHISKSYPTDDQEEEIMRWEEGCMDDEQNRVTHATEQKPCCCLAYDTDLTKSLKDRGKNTAQSSRGRCSSIPERSSHVAAECSAGSFSEEIDDKPSTSNQSDPDFGYRPVRFMRTALQESRISSAILSEEELLDALLLLYHIAVAPNFKQASYYMSHQSQSISLLEETDKQIRERASCDQIKRLKEARNNYKEDVMDCVRHSAWFRISLFSRWKQRGMYALCMWVVQLLLVLSKMDSVFVYIPEFYLESLVDCFHVLRKSDPPFVPSTTFIKQGLSSFITFVVTHFNDSRISNTDLKDLLLQSISVLVQYKEYLEAFENNEAATRHMPAALLAAFDNRSWIPVTNIFLRLCKGSGFSSLKNGESSFSSTVFQALLRDACINDGELLSTFLNRLFNTLSWTITEFSVSVREMQEKYQVMEFQQRKCCVIFELSSNLARVLEFCTYAMPQAFLAGTDTNLRRLTELILFILNHMTSAVDDEFFDLSLRRQGQPSEKVSRGILLAPLVGIILNLLEASEDSKPKQQHDVIGLFASMDCPDTVYYGFQYLLEYNWDGCVSGDDAYVKKLGQLENFLSHLINRASSQEPERKEESFNKDTTDIEDNTCCICYAGEANAMIAPCSHRSCYGCITRHLLNCQRCFFCNATVIDVIRDKEEEEEEDDDGHKRST

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
310	Phosphorylation	PDRSLADTLSRLRRF CCCHHHHHHHHHHHH	22.49	19880383
312	Phosphorylation	RSLADTLSRLRRFAS CHHHHHHHHHHHHCC	31.21	19880383
1019	Phosphorylation	SWTITEFSVSVREMQ HCHHHEEEEEHHHHH	13.78	28011693
1021	Phosphorylation	TITEFSVSVREMQEK HHHEEEEEHHHHHHH	17.79	28011693
1110	Phosphorylation	GQPSEKVSRGILLAP CCCCCCCCHHHHHHH	35.54	23820729

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RKP_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RKP_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RKP_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RKP_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RKP_ARATH

Related Literatures of Post-Translational Modification