dbPTM

RIO2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RIO2_SCHPO
UniProt AC	Q9P7W5
Protein Name	Serine/threonine-protein kinase rio2
Gene Name	rio2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	344
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Required for the final endonucleolytic cleavage of 20S pre-rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity)..
Protein Sequence	MVNLNIKAMRYLSAEDFRTLTAVEMGSRNHEVVPTNMINQIAKIRGGSCTKSLSVLFMHKLIAKVPHISYEGYRLTYAGYDYLALKALSKRASVYSVGNQIGVGKESDVYVVGDQKGKQYILKIHRLGRISFRSVKNNRDYLRNRKTGSWQYLSRLAATKEFAFMKILHEHGFPVPAPIDHSRHCIIMEMIDAFPLRAVTDIRDPPALYQTLMDIIVRFARNGLIHGDFNEFNIIVREDGTAVVIDFPQMVSTSHPDAQFYFDRDVQCIVQYFEKNYQYKGDVPNFEDISKMEKENNLDIMIEASGFNKKQSKELEKYRQEEEKRKENGDDLSDNYEEEEEEKE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
333	Phosphorylation	KENGDDLSDNYEEEE HHCCCCCCCCCHHHH	30.70	28889911
336	Phosphorylation	GDDLSDNYEEEEEEK CCCCCCCCHHHHHHH	29.70	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RIO2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RIO2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RIO2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RIO2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RIO2_SCHPO

Related Literatures of Post-Translational Modification