RHOJ_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RHOJ_MOUSE
• UniProt AC: Q9ER71
• Protein Name: Rho-related GTP-binding protein RhoJ
• Gene Name: Rhoj
• Organism: Mus musculus (Mouse).
• Sequence Length: 214
• Subcellular Localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side .
• Protein Description: GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology..
• Protein Sequence: MSCRERTDSSCGCNGHEENRILKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKGCLGCHGCCAII

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	S-palmitoylation	-----MSCRERTDSS -----CCCCCCCCCC	5.17	-
7	Phosphorylation	-MSCRERTDSSCGCN -CCCCCCCCCCCCCC	35.16	29550500
9	Phosphorylation	SCRERTDSSCGCNGH CCCCCCCCCCCCCCC	27.24	23684622
10	Phosphorylation	CRERTDSSCGCNGHE CCCCCCCCCCCCCCC	19.82	23140645
11	S-palmitoylation	RERTDSSCGCNGHEE CCCCCCCCCCCCCCC	9.25	-
211	Methylation	CLGCHGCCAII---- CCCCCCCEEEC----	3.45	-
211	Farnesylation	CLGCHGCCAII---- CCCCCCCEEEC----	3.45	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RHOJ_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RHOJ_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RHOJ_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RHOJ_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.