RHG26_MOUSE - dbPTM
RHG26_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RHG26_MOUSE
UniProt AC Q6ZQ82
Protein Name Rho GTPase-activating protein 26
Gene Name Arhgap26
Organism Mus musculus (Mouse).
Sequence Length 814
Subcellular Localization Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Colocalizes with actin stress fibers and cortical actin structures..
Protein Description GTPase-activating protein for RHOA and CDC42..
Protein Sequence MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETDDEMCIARSLQEFAAVLRNLEDERSRMIENASEVLITPLEKFRKEQIGAAREAKKKYDKETEKYCGTLEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITMVPFDQKSGGKGGEDESVTLKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNRDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKAASETETDICAEWEIKTVTSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQETRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVPDVPLTNAQLHLSRKKSSDSKPPSCSKRPLTLFHAVPSTEKQEQRNSIINSSLESVSSSANSILNSSSSLQPNLNSSDSNLDVVKPSRPSSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPIRSVAGFVWFSVAAVVLSLAWSSLHAVFSLLVNFVPCHPNLHLLFDRPEEAVREDSSTPFRKAKALYACQAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
152PhosphorylationLEKHLNLSSKKKESQ
HHHHHCCCCHHHHHH		38.7525338131
226PhosphorylationKDFGDFKTQLTISIQ
HHHCCCEEEEEEEEE		28.8924759943
231PhosphorylationFKTQLTISIQNTRNR
CEEEEEEEEECCCCC		16.9424759943
262PhosphorylationENPLEHKTISPYTME
HCCCCCCCCCCCEEE		28.7028576409
371PhosphorylationMDGREPVYNSNRDSQ
HCCCCCCCCCCCCCC		24.4826026062
394DimethylationSIGFSIIRKCIHAVE
HHHHHHHHHHHHHHH		26.56-
425PhosphorylationSRVQKLLSVLMDPKA
HHHHHHHHHHHCHHH		24.52-
454UbiquitinationKTVTSALKTYLRMLP
HHHHHHHHHHHHHCC		34.5422790023
570PhosphorylationNHEKIFNTVPDVPLT
CHHHHHHCCCCCCCC		23.7520415495
577PhosphorylationTVPDVPLTNAQLHLS
CCCCCCCCHHHHHHH		23.5720415495
584PhosphorylationTNAQLHLSRKKSSDS
CHHHHHHHCCCCCCC		31.1622324799
588PhosphorylationLHLSRKKSSDSKPPS
HHHHCCCCCCCCCCC		42.2725266776
591PhosphorylationSRKKSSDSKPPSCSK
HCCCCCCCCCCCCCC		49.3522807455
602PhosphorylationSCSKRPLTLFHAVPS
CCCCCCCEEEECCCC		30.0221183079
609PhosphorylationTLFHAVPSTEKQEQR
EEEECCCCCCCHHHH		42.4729899451
610PhosphorylationLFHAVPSTEKQEQRN
EEECCCCCCCHHHHH		40.9225521595
754PhosphorylationEEAVREDSSTPFRKA
HHHHCCCCCCHHHHH		31.2120469934
755PhosphorylationEAVREDSSTPFRKAK
HHHCCCCCCHHHHHH		53.0420469934
756PhosphorylationAVREDSSTPFRKAKA
HHCCCCCCHHHHHHH		30.3320469934
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RHG26_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RHG26_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RHG26_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of RHG26_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RHG26_MOUSE

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Related Literatures of Post-Translational Modification

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