RHG21_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RHG21_MOUSE
• UniProt AC: Q6DFV3
• Protein Name: Rho GTPase-activating protein 21
• Gene Name: Arhgap21
• Organism: Mus musculus (Mouse).
• Sequence Length: 1944
• Subcellular Localization: Golgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Localization to the Golgi is dependent on interaction with GTP-bound ARF1..
• Protein Description: Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions (By similarity)..
• Protein Sequence: MATHWTGLPEEDGDKLKACGAASACEVSKNKDGKDQGEPVSPSEDEPFSWPGPKTVMLKRTSQGFGFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVAYSQDAYLKGNEAYSGNARNIPEPPPVCYPWLPSTPSATAQPVETCPPDSLPNKQQTSAPVLTQPGRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLANRNNPSGPSHRTEEVRYGVNEQASTKAASRTTSPASVPTAHLIHQTTGSRSLEPSGILLKSGNYSGHSEGISSSRSQAVDSPPVSVNHYSANSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSAADYNQVVPTRTTLQVRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPPVSFNNHRTRSWDYIEGQTEATATVNSESQIPDSNGERKQTYKWSGFTEQDDRRGIHERPRQQEMHKPFRGSNLTVAPVVNSDNRRLVGRGVGPVSQFKKIPPDLRPPHSNRNFPTTTGVSLQRGIAQDRSPLVKVRSNSLKVPPPPVSKPSFSQHSLASMKDQRPVNHLHQHSVLSQQTQFRSESTFEHQLETEVSSCLPGTSAKTSPQLSENLGTSDLELPAIPRNGDINLQEAEIQQPDVLDNKESVILREKPQSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHEIAHIPASAVISASTAHVPSIATVPPSLTTSAPLIRRQLSHDQESVGPPSLDGQHSSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKITDSQKSSEDSGSRKGSSSEVFSDAAREGWLQFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDRREQTTPSEEEQPISVNACLIDISYSETKRRNVFRLTTSDCECLFQAEDRDDMLSWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNSLLSKTEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRRGIPSIVRKTFEKKPAATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLRTLKRLIHDLPEHHFETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEPLTAVQEENTVDSQPVPNIDHLLTNIGRTGVLPGDVSDSATSDSAKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDSVFFKKENTEQSHSEIKEESKRESETSGSKQRVVVAKESNTKKDSGTTKEEKKIPWEEPPPPHSSKRNRSPTLSCRLAMLKEGPRSLLTQKPHCEETGSDSGTLLSTSSQASLLRSSTKKSTSPETKHSEFLSIAGTTTSDYSTTSSTTYLTSLDSSRLSPEVQSVAESKGDEADDERSELVSEGRPVETDSESEFPVFPTTLTSDRLFRGKFQEVARVSRRNSEGSEASCTEGSLTPSLDSRRQQFSSHRLIECDTLSRKKSARFKSDSGSPGDTRTEKETPALAKMFDVMKKGKSTGSLLTPSRSESEKQEATWKTKIADRLKLRPRAPADDMFGVGNQKPTAETAKRKNIKRRHTLGGHRDATEISVLSFWKAHEQSADKESELSAVNRLKPKCSAQDLSISDWLARERVRTSASDLSRGEGLEPQAESPSVLGTPISTHSPPSQQPEARVAATSTLASTSQSPLFTPPQSPDQINRESFQNMSQNASSTANIHPHKQSESPDTKAETPP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	KDQGEPVSPSEDEPF CCCCCCCCCCCCCCC	33.16	25521595
43	Phosphorylation	QGEPVSPSEDEPFSW CCCCCCCCCCCCCCC	50.61	25521595
49	Phosphorylation	PSEDEPFSWPGPKTV CCCCCCCCCCCCEEE	42.97	25619855
61	Phosphorylation	KTVMLKRTSQGFGFT EEEEEEECCCCCCEE	24.66	26745281
62	Phosphorylation	TVMLKRTSQGFGFTL EEEEEECCCCCCEEE	32.13	26745281
68	Phosphorylation	TSQGFGFTLRHFIVY CCCCCCEEEEEEEEE	24.22	23984901
136	Phosphorylation	IIKVNGESVIGKTYS EEEECCEECCCCCHH	22.04	-
248	Phosphorylation	MEIQVPPSPTDVAKS EEEECCCCCCCCCCC	34.07	24453211
250	Phosphorylation	IQVPPSPTDVAKSNT EECCCCCCCCCCCCC	47.66	28066266
310	Phosphorylation	QASTKAASRTTSPAS HHHCCCCCCCCCCCC	34.71	26160508
312	Phosphorylation	STKAASRTTSPASVP HCCCCCCCCCCCCCC	29.18	26160508
313	Phosphorylation	TKAASRTTSPASVPT CCCCCCCCCCCCCCC	31.44	26160508
314	Phosphorylation	KAASRTTSPASVPTA CCCCCCCCCCCCCCH	20.18	27180971
317	Phosphorylation	SRTTSPASVPTAHLI CCCCCCCCCCCHHEE	31.82	30372032
320	Phosphorylation	TSPASVPTAHLIHQT CCCCCCCCHHEEEEC	25.26	26160508
332	Phosphorylation	HQTTGSRSLEPSGIL EECCCCCCCCCCEEE	38.49	21183079
342	Phosphorylation	PSGILLKSGNYSGHS CCEEEEECCCCCCCC	32.04	21183079
345	Phosphorylation	ILLKSGNYSGHSEGI EEEECCCCCCCCCCC	21.39	29514104
355	Phosphorylation	HSEGISSSRSQAVDS CCCCCCCCCCCCCCC	29.21	21183079
370	Phosphorylation	PPVSVNHYSANSHQH CCCCCCCCCCCCCCC	12.32	29514104
389	Phosphorylation	NYKTYKEYIDNRRLH CCCCHHHHHHHCCEE	14.93	29514104
408	Phosphorylation	TIQERLDSLRAASQS HHHHHHHHHHHHHHH	25.09	23649490
419	Phosphorylation	ASQSAADYNQVVPTR HHHHCCHHHHCCCCC	11.63	29514104
427	Phosphorylation	NQVVPTRTTLQVRRR HHCCCCCCEEEEEEC	34.04	23649490
428	Phosphorylation	QVVPTRTTLQVRRRS HCCCCCCEEEEEECC	16.35	23649490
435	Phosphorylation	TLQVRRRSTSHDRVP EEEEEECCCCCCCCC	32.24	26824392
436	Phosphorylation	LQVRRRSTSHDRVPQ EEEEECCCCCCCCCC	28.41	26643407
437	Phosphorylation	QVRRRSTSHDRVPQS EEEECCCCCCCCCCH	25.33	26824392
444	Phosphorylation	SHDRVPQSVQIRQRS CCCCCCCHHHHHHCC	15.21	25777480
451	Phosphorylation	SVQIRQRSVSQERLE HHHHHHCCCCHHHHC	20.13	25266776
453	Phosphorylation	QIRQRSVSQERLEDS HHHHCCCCHHHHCHH	27.80	25521595
460	Phosphorylation	SQERLEDSVLMKYCP CHHHHCHHHHHHHCC	14.05	25266776
469	Phosphorylation	LMKYCPRSASQGALT HHHHCCCCCCCCCCC	19.88	27087446
471	Phosphorylation	KYCPRSASQGALTSP HHCCCCCCCCCCCCC	30.32	27087446
476	Phosphorylation	SASQGALTSPPVSFN CCCCCCCCCCCCCCC	38.36	25619855
477	Phosphorylation	ASQGALTSPPVSFNN CCCCCCCCCCCCCCC	28.23	25619855
481	Phosphorylation	ALTSPPVSFNNHRTR CCCCCCCCCCCCCCC	28.20	25619855
487	Phosphorylation	VSFNNHRTRSWDYIE CCCCCCCCCCCEEEC	22.85	29899451
489	Phosphorylation	FNNHRTRSWDYIEGQ CCCCCCCCCEEECCE	24.56	21183079
548	Methylation	QEMHKPFRGSNLTVA HCCCCCCCCCCCEEE	57.04	-
550	Phosphorylation	MHKPFRGSNLTVAPV CCCCCCCCCCEEEEE	25.14	20415495
553	Phosphorylation	PFRGSNLTVAPVVNS CCCCCCCEEEEEECC	20.90	20415495
568	Methylation	DNRRLVGRGVGPVSQ CCCCCCCCCCCCHHH	29.19	24129315
599	Phosphorylation	FPTTTGVSLQRGIAQ CCCCCCCCCCCCCCC	21.82	27841257
609	Phosphorylation	RGIAQDRSPLVKVRS CCCCCCCCCCEEEEC	30.76	26824392
616	Phosphorylation	SPLVKVRSNSLKVPP CCCEEEECCCCCCCC	33.48	26643407
618	Phosphorylation	LVKVRSNSLKVPPPP CEEEECCCCCCCCCC	30.71	26643407
627	O-linked_Glycosylation	KVPPPPVSKPSFSQH CCCCCCCCCCCCCHH	44.62	30059200
685	Phosphorylation	LPGTSAKTSPQLSEN CCCCCCCCCHHHHHH	45.41	24925903
686	Phosphorylation	PGTSAKTSPQLSENL CCCCCCCCHHHHHHC	15.22	24925903
690	Phosphorylation	AKTSPQLSENLGTSD CCCCHHHHHHCCCCC	21.13	24925903
695	Phosphorylation	QLSENLGTSDLELPA HHHHHCCCCCCCCCC	23.41	26643407
696	Phosphorylation	LSENLGTSDLELPAI HHHHCCCCCCCCCCC	38.10	26643407
736	Phosphorylation	ILREKPQSGRQTPQP EEECCCCCCCCCCCC	44.46	29899451
740	Phosphorylation	KPQSGRQTPQPLRHQ CCCCCCCCCCCCCCC	23.64	26824392
748	Phosphorylation	PQPLRHQSYILAVND CCCCCCCCEEEEEEC	14.17	21082442
850	Phosphorylation	PLIRRQLSHDQESVG HHHHHHCCCCCCCCC	19.38	27087446
855	Phosphorylation	QLSHDQESVGPPSLD HCCCCCCCCCCCCCC	27.09	27742792
860	Phosphorylation	QESVGPPSLDGQHSS CCCCCCCCCCCCCCC	42.07	25619855
866	Phosphorylation	PSLDGQHSSKTERSK CCCCCCCCCCCCHHH	26.16	25619855
867	Phosphorylation	SLDGQHSSKTERSKS CCCCCCCCCCCHHHC	41.28	25619855
872	Phosphorylation	HSSKTERSKSYDEGL CCCCCCHHHCHHCCC	21.52	21659605
874	Phosphorylation	SKTERSKSYDEGLDD CCCCHHHCHHCCCHH	38.78	25521595
875	Phosphorylation	KTERSKSYDEGLDDY CCCHHHCHHCCCHHH	23.04	30635358
882	Phosphorylation	YDEGLDDYREDAKLS HHCCCHHHHHHHCCC	18.64	29899451
889	Phosphorylation	YREDAKLSFKHVSSL HHHHHCCCCEEHHHC	31.38	25338131
894	Phosphorylation	KLSFKHVSSLKGIKI CCCCEEHHHCCCCEE	29.67	22324799
895	Phosphorylation	LSFKHVSSLKGIKIT CCCEEHHHCCCCEEC	32.77	22324799
907	Phosphorylation	KITDSQKSSEDSGSR EECCCCCCCCCCCCC	31.18	26643407
908	Phosphorylation	ITDSQKSSEDSGSRK ECCCCCCCCCCCCCC	53.08	26643407
911	Phosphorylation	SQKSSEDSGSRKGSS CCCCCCCCCCCCCCC	34.32	26643407
913	Phosphorylation	KSSEDSGSRKGSSSE CCCCCCCCCCCCCHH	34.47	26643407
917	Phosphorylation	DSGSRKGSSSEVFSD CCCCCCCCCHHHHHH	33.45	25521595
918	Phosphorylation	SGSRKGSSSEVFSDA CCCCCCCCHHHHHHH	38.90	27742792
919	Phosphorylation	GSRKGSSSEVFSDAA CCCCCCCHHHHHHHH	39.20	25521595
923	Phosphorylation	GSSSEVFSDAAREGW CCCHHHHHHHHHHCC	31.36	29899451
940	Succinylation	FRPLVTDKGKRVGGS EEEEECCCCCCCCCC	57.90	23954790
947	Phosphorylation	KGKRVGGSIRPWKQM CCCCCCCCCCCCCEE	14.97	20415495
962	Phosphorylation	YVVLRGHSLYLYKDR EEEECCCEEEEEECC	22.87	29899451
973	Phosphorylation	YKDRREQTTPSEEEQ EECCCCCCCCCHHCC	35.60	29899451
1056	Phosphorylation	RRIKEYNSLLSKTEQ HHHHHHHHHHHHHHC	29.77	29899451
1067	Phosphorylation	KTEQLPKTPRQSLSI HHHCCCCCHHHHHCH	23.05	29899451
1071	Phosphorylation	LPKTPRQSLSIRQTL CCCCHHHHHCHHHHH	25.93	22324799
1073	Phosphorylation	KTPRQSLSIRQTLLG CCHHHHHCHHHHHHC	22.44	22324799
1077	Phosphorylation	QSLSIRQTLLGAKSE HHHCHHHHHHCCCCC	17.69	22324799
1087	Phosphorylation	GAKSEPKTQSPHSPK CCCCCCCCCCCCCCH	45.02	29895711
1089	Phosphorylation	KSEPKTQSPHSPKEE CCCCCCCCCCCCHHH	29.79	29895711
1092	Phosphorylation	PKTQSPHSPKEESER CCCCCCCCCHHHHHH	40.84	21930439
1097	Phosphorylation	PHSPKEESERKLLSK CCCCHHHHHHHHCCC	43.74	30372032
1103	Phosphorylation	ESERKLLSKDDTSPP HHHHHHCCCCCCCCC	44.46	21149613
1107	Phosphorylation	KLLSKDDTSPPKDKG HHCCCCCCCCCCCCC	53.95	25521595
1108	Phosphorylation	LLSKDDTSPPKDKGT HCCCCCCCCCCCCCC	46.31	25521595
1122	Phosphorylation	TWRRGIPSIVRKTFE CHHCCCCHHHHHHHC	31.62	27180971
1214	Phosphorylation	RDLNVISSLLKSFFR HHHHHHHHHHHHHHH	26.96	28059163
1271	Phosphorylation	FETLKFLSAHLKTVA HHHHHHHHHHHHHHH	19.44	20469934
1276	Phosphorylation	FLSAHLKTVAENSEK HHHHHHHHHHHHHHH	31.17	20469934
1281	Phosphorylation	LKTVAENSEKNKMEP HHHHHHHHHHCCCCC	41.26	20469934
1368	Phosphorylation	LLTNIGRTGVLPGDV HHHHCCCCCCCCCCC	26.82	22871156
1376	Phosphorylation	GVLPGDVSDSATSDS CCCCCCCCCCCCCCC	30.50	26643407
1378	Phosphorylation	LPGDVSDSATSDSAK CCCCCCCCCCCCCHH	26.41	26643407
1380	Phosphorylation	GDVSDSATSDSAKSK CCCCCCCCCCCHHHC	36.70	26643407
1381	Phosphorylation	DVSDSATSDSAKSKG CCCCCCCCCCHHHCC	29.32	26643407
1383	Phosphorylation	SDSATSDSAKSKGSW CCCCCCCCHHHCCCC	37.05	30635358
1389	Phosphorylation	DSAKSKGSWGSGKDQ CCHHHCCCCCCCCCH	31.81	25266776
1392	Phosphorylation	KSKGSWGSGKDQYSR HHCCCCCCCCCHHHH	36.09	29514104
1397	Phosphorylation	WGSGKDQYSRELLVS CCCCCCHHHHHHHHH	21.59	29514104
1411	Phosphorylation	SSIFAAASRKRKKPK HHHHHHHHHCCCCCC	33.34	26824392
1424	Phosphorylation	PKEKAQPSSSEDELD CCHHCCCCCCHHHHH	34.12	21082442
1425	Phosphorylation	KEKAQPSSSEDELDS CHHCCCCCCHHHHHH	44.42	21082442
1426	Phosphorylation	EKAQPSSSEDELDSV HHCCCCCCHHHHHHH	54.10	27087446
1432	Phosphorylation	SSEDELDSVFFKKEN CCHHHHHHHEEECCC	33.19	26745281
1451	Phosphorylation	HSEIKEESKRESETS HHHHHHHHHHHHCCC	37.80	19854140
1470	Phosphorylation	RVVVAKESNTKKDSG EEEEEEECCCCCCCC	49.44	25338131
1472	Phosphorylation	VVAKESNTKKDSGTT EEEEECCCCCCCCCC	49.07	25338131
1501	Phosphorylation	HSSKRNRSPTLSCRL CCCCCCCCCCHHHHH	26.28	25521595
1503	Phosphorylation	SKRNRSPTLSCRLAM CCCCCCCCHHHHHHH	32.33	21659605
1505	Phosphorylation	RNRSPTLSCRLAMLK CCCCCCHHHHHHHHH	10.32	23984901
1591	Phosphorylation	SLDSSRLSPEVQSVA ECCHHCCCHHHHHHH	20.22	27180971
1596	Phosphorylation	RLSPEVQSVAESKGD CCCHHHHHHHHHCCC	28.59	25521595
1610	Phosphorylation	DEADDERSELVSEGR CCCCHHHHHHHHCCC	32.98	26160508
1614	Phosphorylation	DERSELVSEGRPVET HHHHHHHHCCCCCCC	47.13	26160508
1621	Phosphorylation	SEGRPVETDSESEFP HCCCCCCCCCCCCCC	45.09	26160508
1623	Phosphorylation	GRPVETDSESEFPVF CCCCCCCCCCCCCCC	50.90	26160508
1625	Phosphorylation	PVETDSESEFPVFPT CCCCCCCCCCCCCCC	48.79	26160508
1632	Phosphorylation	SEFPVFPTTLTSDRL CCCCCCCCCCCCCCH	23.99	29472430
1633	Phosphorylation	EFPVFPTTLTSDRLF CCCCCCCCCCCCCHH	28.42	29472430
1635	Phosphorylation	PVFPTTLTSDRLFRG CCCCCCCCCCCHHCC	26.87	29472430
1636	Phosphorylation	VFPTTLTSDRLFRGK CCCCCCCCCCHHCCC	24.68	29472430
1651	Phosphorylation	FQEVARVSRRNSEGS HHHHHHHHCCCCCCC	21.70	26824392
1655	Phosphorylation	ARVSRRNSEGSEASC HHHHCCCCCCCCCCC	41.33	25521595
1658	Phosphorylation	SRRNSEGSEASCTEG HCCCCCCCCCCCCCC	26.41	25521595
1661	Phosphorylation	NSEGSEASCTEGSLT CCCCCCCCCCCCCCC	19.95	25619855
1663	Phosphorylation	EGSEASCTEGSLTPS CCCCCCCCCCCCCCC	40.67	25619855
1666	Phosphorylation	EASCTEGSLTPSLDS CCCCCCCCCCCCHHH	23.88	25619855
1668	Phosphorylation	SCTEGSLTPSLDSRR CCCCCCCCCCHHHHH	16.72	25619855
1670	Phosphorylation	TEGSLTPSLDSRRQQ CCCCCCCCHHHHHHH	39.30	25619855
1673	Phosphorylation	SLTPSLDSRRQQFSS CCCCCHHHHHHHHHH	34.36	25619855
1688	Phosphorylation	HRLIECDTLSRKKSA CCEEECHHCCCCCCC	37.99	28066266
1690	Phosphorylation	LIECDTLSRKKSARF EEECHHCCCCCCCCC	44.11	28066266
1694	Phosphorylation	DTLSRKKSARFKSDS HHCCCCCCCCCCCCC	27.93	-
1699	Phosphorylation	KKSARFKSDSGSPGD CCCCCCCCCCCCCCC	34.01	25266776
1701	Phosphorylation	SARFKSDSGSPGDTR CCCCCCCCCCCCCCC	48.54	28066266
1703	Phosphorylation	RFKSDSGSPGDTRTE CCCCCCCCCCCCCCH	29.66	28066266
1707	Phosphorylation	DSGSPGDTRTEKETP CCCCCCCCCCHHHCH	45.46	-
1709	Phosphorylation	GSPGDTRTEKETPAL CCCCCCCCHHHCHHH	54.20	-
1728	Phosphorylation	DVMKKGKSTGSLLTP HHHHHCCCCCCCCCC	46.82	25521595
1729	Phosphorylation	VMKKGKSTGSLLTPS HHHHCCCCCCCCCCC	33.99	25263469
1731	Phosphorylation	KKGKSTGSLLTPSRS HHCCCCCCCCCCCCC	21.94	25777480
1736	Phosphorylation	TGSLLTPSRSESEKQ CCCCCCCCCCHHHHH	43.11	25338131
1789	Phosphorylation	KNIKRRHTLGGHRDA HCCCCCCCCCCCCCC	25.86	27149854
1811	Phosphorylation	FWKAHEQSADKESEL HHHHHHHCCCCHHHH	35.14	28973931
1829	Phosphorylation	NRLKPKCSAQDLSIS HHHCCCCCHHHCCHH	34.78	21183079
1846	Phosphorylation	LARERVRTSASDLSR HHHHHHHCCHHHHHC	26.28	26643407
1847	Phosphorylation	ARERVRTSASDLSRG HHHHHHCCHHHHHCC	18.40	25521595
1849	Phosphorylation	ERVRTSASDLSRGEG HHHHCCHHHHHCCCC	38.56	26643407
1852	Phosphorylation	RTSASDLSRGEGLEP HCCHHHHHCCCCCCC	43.14	26643407
1863	Phosphorylation	GLEPQAESPSVLGTP CCCCCCCCCCCCCCC	26.03	25619855
1865	Phosphorylation	EPQAESPSVLGTPIS CCCCCCCCCCCCCCC	38.97	25619855
1869	Phosphorylation	ESPSVLGTPISTHSP CCCCCCCCCCCCCCC	17.18	25619855
1872	Phosphorylation	SVLGTPISTHSPPSQ CCCCCCCCCCCCCCC	22.67	25619855
1873	Phosphorylation	VLGTPISTHSPPSQQ CCCCCCCCCCCCCCC	27.39	25619855
1875	Phosphorylation	GTPISTHSPPSQQPE CCCCCCCCCCCCCCC	38.30	25619855
1878	Phosphorylation	ISTHSPPSQQPEARV CCCCCCCCCCCCHHH	44.85	25619855
1889	Phosphorylation	EARVAATSTLASTSQ CHHHHHCCCCCCCCC	19.39	25619855
1897	Phosphorylation	TLASTSQSPLFTPPQ CCCCCCCCCCCCCCC	24.28	25619855
1901	Phosphorylation	TSQSPLFTPPQSPDQ CCCCCCCCCCCCHHH	41.56	25619855
1905	Phosphorylation	PLFTPPQSPDQINRE CCCCCCCCHHHCCHH	35.90	25619855

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RHG21_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RHG21_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RHG21_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RHG21_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-874; SER-1424; SER-1425AND SER-1426, AND MASS SPECTROMETRY.
PubMed: 19367708

"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations.";
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
Mol. Cell. Proteomics 6:283-293(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-41, AND MASSSPECTROMETRY.
PubMed: 17114649

"Comprehensive identification of phosphorylation sites in postsynapticdensity preparations.";
Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R.,Burlingame A.L.;
Mol. Cell. Proteomics 5:914-922(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1092, AND MASSSPECTROMETRY.
PubMed: 16452087