dbPTM

RHBD3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RHBD3_MOUSE
UniProt AC	Q8BP97
Protein Name	Rhomboid domain-containing protein 3
Gene Name	Rhbdd3
Organism	Mus musculus (Mouse).
Sequence Length	385
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MHAWEAPGSLSRALPLASSVLMLLLSCLWLLGAGPSLRLAPELLMEPWQVHRLLTHALGHTALPGLLLSLLLLPTLGWWQECHLGTVRFLHNSTVLALATGLLAVLLAGLGVSGAAGGCGYMPVHLAMLAGQSHHPGWPQRTLPPWLLPWLLLALTLLLSSEPPFLQLLCGLLTGLAYAAGAFQWLELSEQRLQVLQEGVLCKSLARCWPLRLFPTPGSLGELPVTYPAGVRPATPRPPYLASSDSWPHSDGSAQLPPRLGPGQLTWKNSERGLDWAGSSFASATTMWAALDEQMLQEGIQASLLDVSVQGSQSSLWLPKPSVSSLRLQQLQHMGFPTEQAAVALAATGRVEGAVSLLVEGLVDTEALVTEGRSSPAHCTGTGAS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
268	Ubiquitination	GPGQLTWKNSERGLD CCCCCEECCCCCCCC	45.41	-
322	Phosphorylation	SLWLPKPSVSSLRLQ CEECCCCCCCHHHHH	40.53	23737553
324	Phosphorylation	WLPKPSVSSLRLQQL ECCCCCCCHHHHHHH	28.17	23737553
325	Phosphorylation	LPKPSVSSLRLQQLQ CCCCCCCHHHHHHHH	18.49	23737553
374	Phosphorylation	ALVTEGRSSPAHCTG HHHCCCCCCCCCCCC	52.08	30352176
375	Phosphorylation	LVTEGRSSPAHCTGT HHCCCCCCCCCCCCC	25.42	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RHBD3_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RHBD3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RHBD3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
NEMO_MOUSE	Ikbkg	physical	24859449
TNAP3_MOUSE	Tnfaip3	physical	24859449

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RHBD3_MOUSE

Related Literatures of Post-Translational Modification