RH3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RH3_ARATH
• UniProt AC: Q8L7S8
• Protein Name: DEAD-box ATP-dependent RNA helicase 3, chloroplastic
• Gene Name: RH3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 748
• Subcellular Localization: Plastid, chloroplast . Plastid, chloroplast stroma .
• Protein Description: Nuclear genome-encoded factor involved in ribosome biogenesis in chloroplasts. [PubMed: 22576849]
• Protein Sequence: MASTVGVPSLYQVPHLEISKPNSKKRSNCLSLSLDKPFFTPLSLVRRTRRIHSSSLLVPSAVATPNSVLSEEAFKSLGLSDHDEYDLDGDNNNVEADDGEELAISKLSLPQRLEESLEKRGITHLFPIQRAVLVPALQGRDIIARAKTGTGKTLAFGIPIIKRLTEEAGDYTAFRRSGRLPKFLVLAPTRELAKQVEKEIKESAPYLSTVCVYGGVSYTIQQSALTRGVDVVVGTPGRIIDLIEGRSLKLGEVEYLVLDEADQMLAVGFEEAVESILENLPTKRQSMLFSATMPTWVKKLARKYLDNPLNIDLVGDQDEKLAEGIKLYAIATTSTSKRTILSDLITVYAKGGKTIVFTQTKRDADEVSLALSNSIATEALHGDISQHQRERTLNAFRQGKFTVLVATDVASRGLDIPNVDLVIHYELPNDPETFVHRSGRTGRAGKEGSAILMHTSSQKRTVRSLERDVGCHFEFISPPTVGDLLESSADQVVATLNGVHPDSIKFFSATAQKLYEEKGTDALAAALAHLSGFSQPPSSRSLLSHEKGWVTLQLIRDPTNARGFLSARSVTGFLSDLYRTAADEVGKIFLIADDRIQGAVFDLPEEIAKELLEKDVPEGNSLSMITKLPPLQDDGPSSDNYGRFSSRDRMPRGGGGSRGSRGGRGGSSRGRDSWGGDDDRGSRRSSGGGSSWSRGGSSSRGSSDDWLIGGRSSSSSRAPSRERSFGGSCFICGKSGHRATDCPDKRGF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
76	Phosphorylation	LSEEAFKSLGLSDHD CCHHHHHHCCCCCCC	22.63	23776212
80	Phosphorylation	AFKSLGLSDHDEYDL HHHHCCCCCCCCCCC	30.97	23776212
85	Phosphorylation	GLSDHDEYDLDGDNN CCCCCCCCCCCCCCC	28.06	23776212
105	Phosphorylation	DGEELAISKLSLPQR CCCEEEEHHCCCCHH	23.18	24243849
702	Phosphorylation	GGSSSRGSSDDWLIG CCCCCCCCCCCCEEC	29.50	29654922
703	Phosphorylation	GSSSRGSSDDWLIGG CCCCCCCCCCCEECC	42.27	25561503
716	Phosphorylation	GGRSSSSSRAPSRER CCCCCCCCCCCCCCC	34.12	19376835
724	Phosphorylation	RAPSRERSFGGSCFI CCCCCCCCCCCCEEE	24.40	14593172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RH3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RH3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RH3_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RH3_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-80; SER-716 AND SER-724,AND MASS SPECTROMETRY.
PubMed: 19376835