RGAP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RGAP2_ARATH
• UniProt AC: F4JI46
• Protein Name: Rho GTPase-activating protein 2
• Gene Name: ROPGAP2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 430
• Protein Description: Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state..
• Protein Sequence: MTGLVMMTKGGGCGGGGKGGRRKSTAEEEEEEEQNQQQLSLVEFLLTALRKSVVSCRVDNRQDDGGVGGGISSAVHHMEIGWPTNVRHITHVTFDRFHGFLGLPHELQVEIPCRVPSASVSVFGVSAESMQCSYDEKGNSVPTILLLMQERLYSQQGLKAEGIFRINPENSQEEHVRDQLNRGIVPENIDVHCLAGLIKAWFRELPSGVLDGLSPEEVLNCNTEDESVELIKQLKPTESALLNWAVDLMADVVEEEESNKMNARNIAMVFAPNMTQMTDPLTALMHAVQVMNLLKTLITKTLAEREENATGSEGYSPSHSSNSQTDSDSDNAQDMEVSCESQATDSECGEEEEVEEVEQHQEHLSRHSTHEDETDIGSLCSIEKCFLNQLNNNAARVSNTSISEDWSPKAFPLVSFTENKSNTLSSSTSD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MTGLVMMTKGGGCGG CCCEEEEECCCCCCC		24894044
119	Phosphorylation	PCRVPSASVSVFGVS ECCCCCCEEEEEEEC		28011693
121	Phosphorylation	RVPSASVSVFGVSAE CCCCCEEEEEEECCC		28011693
296	Phosphorylation	QVMNLLKTLITKTLA HHHHHHHHHHHHHHH		19880383
407	Phosphorylation	TSISEDWSPKAFPLV CCCCCCCCCCCCCEE		30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RGAP2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RGAP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RGAP2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RGAP2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.