RFXAP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RFXAP_MOUSE
• UniProt AC: Q8VCG9
• Protein Name: Regulatory factor X-associated protein
• Gene Name: Rfxap
• Organism: Mus musculus (Mouse).
• Sequence Length: 231
• Subcellular Localization: Nucleus.
• Protein Description: Part of the RFX complex that binds to the X-box of MHC II promoters..
• Protein Sequence: MEAQAVPEGSGPSTASPRTAPPVTVLVMRQDEAEADGALRPGLAGSEAAADAEDEAGDDDADLLDTSDPAGGGESAASPEELEDEDAEGGGAARRRGSKTCTYEGCRETTSQVAKQRKPWMCKKHRNKMYKDKYKKKKSDQALGSGGPSAASTGNVKLEESTDNILSIVKQRTGSFGDRPARPTLLEQVLNQKRLSLLRSPEVVQFLQKQQQLLNQQVLEQRQQHFPGAPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	AQAVPEGSGPSTASP CCCCCCCCCCCCCCC	45.96	26643407
13	Phosphorylation	VPEGSGPSTASPRTA CCCCCCCCCCCCCCC	39.88	26643407
14	Phosphorylation	PEGSGPSTASPRTAP CCCCCCCCCCCCCCC	34.00	25293948
16	Phosphorylation	GSGPSTASPRTAPPV CCCCCCCCCCCCCCE	18.27	26643407
139	Phosphorylation	DKYKKKKSDQALGSG HHHHHHHHHHCCCCC	43.78	28285833
196	Phosphorylation	VLNQKRLSLLRSPEV HHCHHHHHHHCCHHH	29.41	28725479
200	Phosphorylation	KRLSLLRSPEVVQFL HHHHHHCCHHHHHHH	25.94	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RFXAP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RFXAP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RFXAP_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RFXAP_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.