dbPTM

RFC3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RFC3_MOUSE
UniProt AC	Q8R323
Protein Name	Replication factor C subunit 3
Gene Name	Rfc3
Organism	Mus musculus (Mouse).
Sequence Length	356
Subcellular Localization	Nucleus .
Protein Description	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1..
Protein Sequence	MSLWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQQYPFTEDQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MSLWVDKYRPSSLAR CCCCCCCCCCCHHHH	24.24	28059163
11	Phosphorylation	WVDKYRPSSLARLDY CCCCCCCCHHHHCCC	29.05	27600695
12	Phosphorylation	VDKYRPSSLARLDYH CCCCCCCHHHHCCCC	28.82	24719451
20	Acetylation	LARLDYHKEQAAQLR HHHCCCCHHHHHHHH	45.34	-
76	Phosphorylation	IEHQTITTPSKKKIE EEEEEEECCCCCCEE	23.01	28418008
91	Phosphorylation	ISTIASNYHLEVNPS EEEECCCEEEECCHH	12.80	-
125	Phosphorylation	SQQLETSSQRDFKVV HHCCCCCCCCCCEEE	36.33	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RFC3_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RFC3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RFC3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RFC3_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RFC3_MOUSE

Related Literatures of Post-Translational Modification