| UniProt ID | RFC2_MOUSE | |
|---|---|---|
| UniProt AC | Q9WUK4 | |
| Protein Name | Replication factor C subunit 2 | |
| Gene Name | Rfc2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 349 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity).. | |
| Protein Sequence | MEVQESGCDPSESGAQEPSPVPSKTAGHYELPWVEKYRPLKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKILAHLWHLGYSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MEVQESGC -------CCCCCCCC | 11.68 | - | |
| 6 | Phosphorylation | --MEVQESGCDPSES --CCCCCCCCCCCCC | 27.85 | 25619855 | |
| 11 | Phosphorylation | QESGCDPSESGAQEP CCCCCCCCCCCCCCC | 31.01 | 28066266 | |
| 13 | Phosphorylation | SGCDPSESGAQEPSP CCCCCCCCCCCCCCC | 43.71 | 25619855 | |
| 19 | Phosphorylation | ESGAQEPSPVPSKTA CCCCCCCCCCCCCCC | 37.46 | 26824392 | |
| 23 | Phosphorylation | QEPSPVPSKTAGHYE CCCCCCCCCCCCCCC | 42.76 | 25619855 | |
| 140 | Phosphorylation | IILDEADSMTDGAQQ EEEECHHHCCHHHHH | 30.54 | 28285833 | |
| 142 | Phosphorylation | LDEADSMTDGAQQAL EECHHHCCHHHHHHH | 34.92 | 28285833 | |
| 158 | Acetylation | RTMEIYSKTTRFALA HHHHHHCCHHHHHHH | 36.62 | - | |
| 171 | Acetylation | LACNASDKIIEPIQS HHCCCCCHHHHHHHH | 42.99 | 23806337 | |
| 178 | Phosphorylation | KIIEPIQSRCAVLRY HHHHHHHHCCCHHHC | 30.01 | 30482847 | |
| 259 | Ubiquitination | EPHPLLVKEMIQHCV CCCCHHHHHHHHHHH | 41.35 | - | |
| 299 | Acetylation | GNIFRVCKTFPMAEY HHHHHHHCCCCHHHH | 50.79 | - | |
| 349 | Phosphorylation | KTMAPVAS------- HHCCCCCC------- | 40.77 | 30482847 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RFC2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RFC2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RFC2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RFC2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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