RFA1B_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RFA1B_ARATH
• UniProt AC: Q9SD82
• Protein Name: Replication protein A 70 kDa DNA-binding subunit B
• Gene Name: RPA1B
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 604
• Subcellular Localization: Nucleus.
• Protein Description: Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity). Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity)..
• Protein Sequence: MENSVTQDGIATVLANQSLDSSSVRPEIVVQVVDLKPAGNRYTFSANDGKMKIKAMLPATLTSDIISGKIQNLGLIRLLEYTVNDIPGKSEEKYMLITKCEAVASALDSEIKAEIKASTGIMLKPKHEFVAKSASQIINEQRGNAAPAARMAMTRRVHPLVSLNPYQGSWTIKVRVTNKGVMRTYKNARGEGCVFNVELTDEEGTQIQATMFNAAARKFYDRFEMGKVYYISRGSLKLANKQFKTVQNDYEMTLNENSEVEEASNEEMFTPETKFNFVPIDELGTYVNQKDLIDVIGVVQSVSPTMSIRRKNDNEMIPKRDITLADETKKTVVVSLWNDLATGIGQELLDMADNHPVIAIKSLKVGAFQGVSLSTISRSNVVINPNSPEATKLKSWYDAEGKETSMSAIGSGMSSSANNGSRSMYSDRVFLSHITSNPSLGEEKPVFFSTRAYISFIKPDQTMWYRACKTCNKKVTEAMDSGYWCESCQKKDQECSLRYIMAVKVSDSTGETWLSAFNDEAEKIIGCTADDLNDLKSEEGEVNEFQTKLKEATWSSHLFRISVSQQEYNSEKRQRITVRGVSPIDFAAETRLLLQDISKNKTSQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
405	Phosphorylation	DAEGKETSMSAIGSG CCCCCCCCHHHCCCC		27531888
407	Phosphorylation	EGKETSMSAIGSGMS CCCCCCHHHCCCCCC		27531888
411	Phosphorylation	TSMSAIGSGMSSSAN CCHHHCCCCCCCCCC		27531888
414	Phosphorylation	SAIGSGMSSSANNGS HHCCCCCCCCCCCCC		27531888
415	Phosphorylation	AIGSGMSSSANNGSR HCCCCCCCCCCCCCC		27531888
416	Phosphorylation	IGSGMSSSANNGSRS CCCCCCCCCCCCCCC		27531888

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RFA1B_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RFA1B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RFA1B_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RFA1B_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.