dbPTM

REXO4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	REXO4_SCHPO
UniProt AC	O94375
Protein Name	RNA exonuclease 4
Gene Name	rex4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	260
Subcellular Localization	Nucleus.
Protein Description	Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity)..
Protein Sequence	MSSSNWEKLKKKLDSAKSGRVEKKHSNEKKYLKSVKGKNNENENSYIVDKKRMNELKKFAKENDIPESQVLDAYGVDASKLTRKTNLETLGKYIAMDCEMVGVADDMSVLARVSIVNYHGHVVYDTYVRPKEKVTDWRTWVSGVKSFHMRDAPSFEKVQAEVAKILDNRVLVGHAVHNDLKVLLLSHPRRMIRDTSRFSGYRKLAKGRTPGLKKLAEVILGRDIQSGQHSSVQDAQATMELYKKVKKEMDEVAFKGLSKS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
45	Phosphorylation	KNNENENSYIVDKKR CCCCCCCCCCCCHHH	15.28	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of REXO4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of REXO4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of REXO4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of REXO4_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of REXO4_SCHPO

Related Literatures of Post-Translational Modification