REXO4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: REXO4_MOUSE
• UniProt AC: Q6PAQ4
• Protein Name: RNA exonuclease 4
• Gene Name: Rexo4
• Organism: Mus musculus (Mouse).
• Sequence Length: 432
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: May function as an exonuclease..
• Protein Sequence: MCACAVAGVAVSSLVVPTAESGEMKTKATAPVPQPGPIRKLARKKAKKKFRKSKALAGSGVPGSHPAAVAGRPPKAPENFSQNWKALQELLKQKSQAAEKPLVSQMDDKMHPQIIQQNRKKASDKSKGDKQRTEKAKSTRGSVTSAPTDRKILVPPTDTSGTEQKKGAKKRTYSDISSHQGALKPKWKATEAAVILNQPTPTEEDIWFDDVDPDDIEDAIGPEAAMLVRKRLGQKKRTISLEKEQAFGGLTKALALDCEMVGVGPKGEESIAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQGEEFEVVKKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKFKPFRSRVKSGRPSLKRLSEKILGIRVQQAEHCSIQDAQAAMRLYVMVKREWESSTANRRAPAATPQHRIKNS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	KSKALAGSGVPGSHP HHHHHCCCCCCCCCH	30.89	21454597
64	Phosphorylation	AGSGVPGSHPAAVAG CCCCCCCCCHHHHCC	21.89	21454597
123	Phosphorylation	QQNRKKASDKSKGDK HHHHHHHHCCCCCHH	55.22	-
138	Phosphorylation	QRTEKAKSTRGSVTS HHHHHHHHCCCCCCC	28.35	29176673
142	Phosphorylation	KAKSTRGSVTSAPTD HHHHCCCCCCCCCCC	20.94	29176673
144	Phosphorylation	KSTRGSVTSAPTDRK HHCCCCCCCCCCCCC	22.37	29176673
145	Phosphorylation	STRGSVTSAPTDRKI HCCCCCCCCCCCCCE	30.05	29176673
174	Phosphorylation	GAKKRTYSDISSHQG CCCCCCHHHHHHCCC	28.05	28418008
177	Phosphorylation	KRTYSDISSHQGALK CCCHHHHHHCCCCCC	27.10	29176673
238	Phosphorylation	RLGQKKRTISLEKEQ HHCCCCCEEEHHHHH	24.65	28725479
240	Phosphorylation	GQKKRTISLEKEQAF CCCCCEEEHHHHHHH	29.84	29514104
251	Phosphorylation	EQAFGGLTKALALDC HHHHCCHHHHHHHCC	19.97	-
321	Acetylation	GEEFEVVKKEVAEML CCCEEHHHHHHHHHH	48.68	23864654
424	Phosphorylation	NRRAPAATPQHRIKN CCCCCCCCCCHHCCC	26.11	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of REXO4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of REXO4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of REXO4_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of REXO4_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.