REM2_HUMAN - dbPTM
REM2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID REM2_HUMAN
UniProt AC Q8IYK8
Protein Name GTP-binding protein REM 2
Gene Name REM2
Organism Homo sapiens (Human).
Sequence Length 340
Subcellular Localization Cell membrane .
Protein Description Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis..
Protein Sequence MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MHTDLDTDMD
-----CCCCCCCCCC		36.6424043423
7Phosphorylation-MHTDLDTDMDMDTE
-CCCCCCCCCCCCCC		40.2924043423
13PhosphorylationDTDMDMDTETTALCP
CCCCCCCCCCEEECC		28.7024043423
15PhosphorylationDMDMDTETTALCPSG
CCCCCCCCEEECCCC		21.3324043423
16PhosphorylationMDMDTETTALCPSGS
CCCCCCCEEECCCCC		16.0524043423
21PhosphorylationETTALCPSGSRRASP
CCEEECCCCCCCCCC		48.6924043423
23PhosphorylationTALCPSGSRRASPPG
EEECCCCCCCCCCCC		23.9624043423
27PhosphorylationPSGSRRASPPGTPTP
CCCCCCCCCCCCCCH		29.8026657352
31PhosphorylationRRASPPGTPTPEADA
CCCCCCCCCCHHHHH		29.7526657352
33PhosphorylationASPPGTPTPEADATL
CCCCCCCCHHHHHHH		33.3329691806
54PhosphorylationLLAELDRSGLPSAPG
HHHHHHHCCCCCCCC		44.3324719451
68PhosphorylationGAPRRRGSMPVPYKH
CCCCCCCCCCCCHHH		20.3627251275
73PhosphorylationRGSMPVPYKHQLRRA
CCCCCCCHHHHHHHC		22.72-
128PhosphorylationGESGVGKSTLAGTFG
ECCCCCHHHHCCCCC		23.7925954137
129PhosphorylationESGVGKSTLAGTFGG
CCCCCHHHHCCCCCC		24.9025954137
168PhosphorylationEEVTLVVYDIWEQGD
HHEEEEEEECHHCCC		8.33-
202PhosphorylationFSVTDRRSFSKVPET
EEECCCCCCCCCCHH		34.4624719451
258PhosphorylationLSCKHIETSAALHHN
EECCCCHHCHHHCCC		24.0629449344
259PhosphorylationSCKHIETSAALHHNT
ECCCCHHCHHHCCCH		9.9629449344
266PhosphorylationSAALHHNTRELFEGA
CHHHCCCHHHHHHHH		22.5929449344
295PhosphorylationGQRPDPGSPEGPAPP
CCCCCCCCCCCCCCC		25.7625849741
307PhosphorylationAPPARRESLTKKAKR
CCCHHHHHHHHHHHH		39.2628348404
309PhosphorylationPARRESLTKKAKRFL
CHHHHHHHHHHHHHH		39.5228348404
331PhosphorylationAKFFKQRSRSCHDLS
HHHHHHHCCCCCCCC		26.5023312004
333PhosphorylationFFKQRSRSCHDLSVL
HHHHHCCCCCCCCCC		19.6330266825
338PhosphorylationSRSCHDLSVL-----
CCCCCCCCCC-----		27.6830266825
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of REM2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of REM2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of REM2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of REM2_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of REM2_HUMAN

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Related Literatures of Post-Translational Modification

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