REBL1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: REBL1_MOUSE
• UniProt AC: Q9D8T3
• Protein Name: GTPase RhebL1
• Gene Name: Rhebl1
• Organism: Mus musculus (Mouse).
• Sequence Length: 184
• Subcellular Localization: Endomembrane system ; Lipid-anchor ; Cytoplasmic side . Cytoplasm .
• Protein Description: Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2 (By similarity)..
• Protein Sequence: MPLVRYRKVAILGYRSVGKTSLAHQFVEGEFLEGYDPTVENTYSKTVTLGKDEFHLHLVDTAGQDEYSILPYSLIIGVHGYVLVYSVNSLRSFQIVKNLYQKLHEGHGKTRLSVLLVGNKADLSPEREVQAVEGKKLAESWGAMFMESSARDNQLTQDVFIKVIQEIARVENSYGRQDRRCYLM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
162	Ubiquitination	LTQDVFIKVIQEIAR CCHHHHHHHHHHHHH	23.09	-
181	Methylation	YGRQDRRCYLM---- CCCCCCCEEEC----	2.97	-
181	Farnesylation	YGRQDRRCYLM---- CCCCCCCEEEC----	2.97	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of REBL1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of REBL1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of REBL1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of REBL1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.