RDM4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RDM4_ARATH
• UniProt AC: Q8GYP3
• Protein Name: RNA-directed DNA methylation 4
• Gene Name: RDM4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 346
• Protein Description: Probable regulatory factor for several RNA polymerases. Effector involved in facilitation of Pol V transcription as RNA scaffold and recruitment of silencing complex to target genomic sites..
• Protein Sequence: MDGVGESSTQNEVEEKPVIVRVKRKVGQSLLDAFWLEINERPLKRPTLDFSKLSISDSGERGPSVAEDVKPKKVLVRHLETVTDSETTADIIHSFFESDHNEKSCSKGKFEERKIAFKKDNRKEQRLTKSVQKQQIASENARFEQIWRSRKGNKEGIHEKCHFFDVIRVDTEERRDNAQEFTSLEDQKMLASFLPLLRECIPTAAEEIEADIQSSHTEEYVYDYYAVNEEMDISEDSSKNQFPLVIVEDEEEFCDGSDESDYDSEDSNAEDHPKTDYPEEEEEEEEEDDDDDDDDESEEEKSEASDESDDEETSKRHVRSVLGDDEFDDYAEDVYGYSESDEEFES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDGVGESS -------CCCCCCCC		22223895
340	Phosphorylation	DVYGYSESDEEFES- HHHCCCCCHHHHCC-		27531888
346	Phosphorylation	ESDEEFES------- CCHHHHCC-------		27531888

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RDM4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RDM4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RDM4_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RDM4_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.