dbPTM

RCOR_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RCOR_CAEEL
UniProt AC	Q18919
Protein Name	REST corepressor spr-1
Gene Name	spr-1 {ECO:0000312\|WormBase:D1014.8}
Organism	Caenorhabditis elegans.
Sequence Length	558
Subcellular Localization	Nucleus .
Protein Description	Probable corepressor protein, which probably participates in the transcriptional repression of the presenilin protein hop-1. [PubMed: 12381669 Probably acts via the formation of a multiprotein complex that deacetylates and demethylates specific sites on histones]
Protein Sequence	MDLYDDDGESAQSEKVDVPSEESTIAGPETDIPAETIEENVPEVEENTLLEEDSLVDVDSPRPSQQRSKPSKSKRKRKRSSSGESSAAEPEIDAGAKVKGPLSNTNKEINVGTEFQAKIADLNLNDKACNEDRDDQDELIWNTPETIDDEKLEAFIRESSDRYLIPIDRALYILTINNFNFDSAIAEVARRNELKDVWTDQEITLFENCYQIFGKNFSQIRSALCHRSLQSIVQFYYESKKRVKYLNFVNSKCDDSSSSEETETPSPYPEAIFESMCDNCGEKAENMQINNAMNRPECRACLIYFNQTGVPRPTSLRLVLAERIRNQVSCPDNMKEYMKDFDKLSAQATGSTFQKRIIVKDQCVEYIIDVDKIPSSSCTENGNVGETSSPSAQKTEIQSESDGSGPLIWRHKKTVCMEEIEVLADDSRRKMFEACQHGSKVDIKLVASWKNDMTNLRKRVEQTYYDPDLNPTYLFSHDRVHYSQDWTQLERSQVIRCFNMYGAHFEHIADVIGTKTPDQVYQFYLENQKAIDAADEEFLADMKNPERLADMEEEEDSI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of RCOR_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RCOR_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RCOR_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RCOR_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RCOR_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RCOR_CAEEL

Related Literatures of Post-Translational Modification