dbPTM

RCN1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RCN1_MOUSE
UniProt AC	Q05186
Protein Name	Reticulocalbin-1
Gene Name	Rcn1
Organism	Mus musculus (Mouse).
Sequence Length	325
Subcellular Localization	Endoplasmic reticulum lumen.
Protein Description	May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment..
Protein Sequence	MARGGRLGLALGLLLALVLALRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKLWIKRVQKRYIYDNVAKVWKDYDRDKDEKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKASDLDGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
47	N-linked_Glycosylation	GERPPEDNQSFQYDH CCCCCCCCCCCCCCH	37.42	-
49	Phosphorylation	RPPEDNQSFQYDHEA CCCCCCCCCCCCHHH	22.14	-
65	Phosphorylation	LGKEDSKTFDQLSPD CCCCCCCCHHHCCCH	36.07	25159016
70	Phosphorylation	SKTFDQLSPDESKER CCCHHHCCCHHHHHH	25.36	26160508
74	Phosphorylation	DQLSPDESKERLGKI HHCCCHHHHHHHHHH	47.39	25159016
87	Phosphorylation	KIVDRIDSDGDGLVT HHHHHHCCCCCCCCC	40.91	26525534
142	Phosphorylation	KQATYGYYLGNPAEF HHHHCCCCCCCHHHC	12.08	-
284	Phosphorylation	AEARHLVYESDKNKD HHHHHHHHHCCCCHH	18.97	22817900
286	Phosphorylation	ARHLVYESDKNKDEM HHHHHHHCCCCHHHC	35.88	26525534

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RCN1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RCN1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RCN1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RCN1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RCN1_MOUSE

Related Literatures of Post-Translational Modification