RCBT2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RCBT2_MOUSE
• UniProt AC: Q99LJ7
• Protein Name: RCC1 and BTB domain-containing protein 2
• Gene Name: Rcbtb2
• Organism: Mus musculus (Mouse).
• Sequence Length: 551
• Subcellular Localization: Cytoplasmic vesicle, secretory vesicle, acrosome . Mainly found in the acrosomal cap region.
• Protein Sequence: MEEEVPGFYGESGKSVQATLSSLKMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCSGCLGVGDIQSTIEPRRLDSLTGKKIASLSYGSGPHIVLATTDGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTANQPIPRRVTGCLQNKVVMNIACGQMCSMAVVDTGEVYVWGYNGNGQLGLGSSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQIYAWGANSYGQLGTGNKSNQSYPTPVVVEKDRIIEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHHTHFCCTDDVFACFATPAVTWRLLSVEPDDHLTVAESLKREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFRSSLEDSEDDIVEMSEFSYPVFRAFLEYLYTDNISLSPEEAVGLLDLATFYSETRLKKLCQQTIKQGICEENAIALLSAAVKYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLLKNFISKASRVGAFKN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	KSVQATLSSLKMLDV CCHHHHHHHCCCCCC	29.30	27149854
147	Ubiquitination	LVPCHISTNLSNKQV EEECEEECCCCCCCE	39.31	27667366
283	Ubiquitination	GQIYAWGANSYGQLG CCEEEEECCCCCCCC	7.35	27667366
295	Phosphorylation	QLGTGNKSNQSYPTP CCCCCCCCCCCCCCC	44.06	30482847
307	Ubiquitination	PTPVVVEKDRIIEIA CCCEEEECCCEEEEE	40.47	27667366
307	Ubiquitination	PTPVVVEKDRIIEIA CCCEEEECCCEEEEE	40.47	22790023
382	Ubiquitination	DDHLTVAESLKREFD CCCCHHHHHHHHHCC	52.87	27667366
403	Ubiquitination	LKFLVDGKYIYAHKV EEEEECCEEEEEEEE	24.82	-
403	Ubiquitination	LKFLVDGKYIYAHKV EEEEECCEEEEEEEE	24.82	22790023
518	Ubiquitination	CFRFCINHLTVVTQT HHHHHHHCCEEEEEC	11.72	27667366
541	Phosphorylation	DLLKNFISKASRVGA HHHHHHHHHHHHHCC	20.31	-
542	Ubiquitination	LLKNFISKASRVGAF HHHHHHHHHHHHCCC	45.63	27667366
542	Ubiquitination	LLKNFISKASRVGAF HHHHHHHHHHHHCCC	45.63	22790023
544	Phosphorylation	KNFISKASRVGAFKN HHHHHHHHHHCCCCC	31.10	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RCBT2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RCBT2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RCBT2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RCBT2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.