dbPTM

RBMX2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RBMX2_MOUSE
UniProt AC	Q8R0F5
Protein Name	RNA-binding motif protein, X-linked 2
Gene Name	Rbmx2
Organism	Mus musculus (Mouse).
Sequence Length	326
Subcellular Localization
Protein Description
Protein Sequence	MNPLTKVKLINELNEREVQLGVAEKVSWHSEYKHSAWIFVGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTVLAVDNFNGIKIKGRTIRVDHVSNYRAPQESEDVDDVTRELQEKGCGVKTPPSSPPEVSEDEDAKLTKKHKKDKKEKKKRKKEKTEGQAQAEQPSCSRSATVKEKKDERASRKHSSKTSERAQKSEHRESKKSHSGSPDGRSSYHARAEDPECKARKEKPKHEHKSASRREAEEKSRERERGRSSGTHSGRHRGHSDGRSHRSRSRSRSPDKSHRHKKYRHSRERDSYHGSDRRHH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
140	Phosphorylation	EKGCGVKTPPSSPPE HCCCCCCCCCCCCCC	37.72	25521595
143	Phosphorylation	CGVKTPPSSPPEVSE CCCCCCCCCCCCCCC	57.59	27087446
144	Phosphorylation	GVKTPPSSPPEVSED CCCCCCCCCCCCCCC	50.69	25521595
149	Phosphorylation	PSSPPEVSEDEDAKL CCCCCCCCCCHHHHH	37.35	25521595
157	Phosphorylation	EDEDAKLTKKHKKDK CCHHHHHHHHHHHHH	37.02	21659605
223	Phosphorylation	EHRESKKSHSGSPDG HHHHHHHHCCCCCCC	26.99	23375375
225	Phosphorylation	RESKKSHSGSPDGRS HHHHHHCCCCCCCCC	48.32	23684622
227	Phosphorylation	SKKSHSGSPDGRSSY HHHHCCCCCCCCCCC	23.88	22817900
232	Phosphorylation	SGSPDGRSSYHARAE CCCCCCCCCCHHCCC	40.55	23684622
233	Phosphorylation	GSPDGRSSYHARAED CCCCCCCCCHHCCCC	21.41	29550500
234	Phosphorylation	SPDGRSSYHARAEDP CCCCCCCCHHCCCCH	10.76	29550500
274	Phosphorylation	RERERGRSSGTHSGR HHHHHHCCCCCCCCC	35.62	27717184
286	Phosphorylation	SGRHRGHSDGRSHRS CCCCCCCCCCCCCCC	44.58	28059163
309	Phosphorylation	KSHRHKKYRHSRERD CCHHHHHHCHHHHCC	20.54	27717184
312	Phosphorylation	RHKKYRHSRERDSYH HHHHHCHHHHCCCCC	27.17	27717184
321	Phosphorylation	ERDSYHGSDRRHH-- HCCCCCCCCCCCC--	18.03	27841257

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RBMX2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RBMX2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RBMX2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RBMX2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RBMX2_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-140 AND SER-149, ANDMASS SPECTROMETRY.	17242355 [Abstract]