dbPTM

RBM34_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RBM34_MOUSE
UniProt AC	Q8C5L7
Protein Name	RNA-binding protein 34
Gene Name	Rbm34
Organism	Mus musculus (Mouse).
Sequence Length	375
Subcellular Localization	Nucleus, nucleolus.
Protein Description
Protein Sequence	MALGGEERKRRKGSERRQSSGDGVSCAASDYLVGQVADSLRGGPRPPGGGTGRLAALFSTAEPSAPPVFVPVPQETSKKRKLDDDDDDEEESVSQTKKPVLQEPSRKVKVKKLSDADKRLANRESALASADLEEELHQDQGQGRRRRSQSRGKVADGEALDVALSLAKDGGQRTKIPVNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPAEGTLTKKLAAIKRKFHPDQKSINAYVVFKDESAAAKALQRNGAQIAEGFRIRVDLASETASRDKRSVFVGNLPYKIEDSALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVNKEKLKQQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	ERKRRKGSERRQSSG HHHCCCCCCCCHHCC	30.85	26745281
19	Phosphorylation	KGSERRQSSGDGVSC CCCCCCHHCCCCCCH	34.18	27087446
20	Phosphorylation	GSERRQSSGDGVSCA CCCCCHHCCCCCCHH	32.34	25521595
25	Phosphorylation	QSSGDGVSCAASDYL HHCCCCCCHHHHHHH	11.99	21082442
29	Phosphorylation	DGVSCAASDYLVGQV CCCCHHHHHHHHHHH	14.30	25619855
31	Phosphorylation	VSCAASDYLVGQVAD CCHHHHHHHHHHHHH	10.78	25619855
39	Phosphorylation	LVGQVADSLRGGPRP HHHHHHHHHCCCCCC	15.38	25619855
51	Phosphorylation	PRPPGGGTGRLAALF CCCCCCCCHHHHHHH	23.54	28059163
92	Phosphorylation	DDDDEEESVSQTKKP CCCCCHHHHHHCCCC	30.28	25619855
94	Phosphorylation	DDEEESVSQTKKPVL CCCHHHHHHCCCCHH	41.22	25619855
114	Phosphorylation	KVKVKKLSDADKRLA CEEEEECCHHHHHHH	39.36	28066266
125	Phosphorylation	KRLANRESALASADL HHHHHHHHHHHHCCH	25.91	30635358
129	Phosphorylation	NRESALASADLEEEL HHHHHHHHCCHHHHH	24.14	30635358
153	Acetylation	RRSQSRGKVADGEAL HHHHHCCCCCCHHHH	32.89	23806337
153	Acetylation	RRSQSRGKVADGEAL HHHHHCCCCCCHHHH	32.89	-
292	Phosphorylation	TASRDKRSVFVGNLP CCCCCCCEEEEECCC	26.16	-
377	Phosphorylation	EKLKQQ--------- HHHHCC---------		29514104
418	Acetylation	-------------------------------------------------- --------------------------------------------------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RBM34_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RBM34_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RBM34_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RBM34_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RBM34_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25, AND MASSSPECTROMETRY.	17242355 [Abstract]