RBA50_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RBA50_SCHPO
• UniProt AC: O43088
• Protein Name: RNA polymerase II-associated protein rba50
• Gene Name: rba50
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 452
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation..
• Protein Sequence: MENHRSVFSNVIGDIVEKPPKQLVEVKRSVQRHARGFPAVSRTLPKRESKSMSAYKEKMLRKNKESPGLEGKGNLDDQGIDEENRVRLERMNDLEIEGAQEEIRATIRDDLLEMLKKRAFKKKAERELAQRKDRSSQVNTPDLSQRPSDDSFLSNEKLRSSEKLNRNLQSVLSSEAVDSSSGSPSPPMALSQAEIRSRQTKRVMFPDKAEELTKIFSLPTLAPIKGNEEDDASEDAKHSPKKHSPALSDGTTSNDGAPLEFDTTHLPEKQVTLDPNDPSFYEQLHDKYFPNLPVDEKQMQWLHDPSPAENSYHPSVESLHAHEIRFGFKGEIITPSQSQTIPVNEGLHHHGDAPFSAGYTLVELAHLLRSSFPTQRCIAIQTIGRIIYRLNSGEFREVLSPELHTLVEDAHIYELLAAAASDQVKHLTVRSLAIEALWLCSQSQHGSSRSAV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
66	Phosphorylation	MLRKNKESPGLEGKG HHHHCCCCCCCCCCC	26.36	24763107
135	Phosphorylation	LAQRKDRSSQVNTPD HHHHHCCCCCCCCCC	34.94	24763107
136	Phosphorylation	AQRKDRSSQVNTPDL HHHHCCCCCCCCCCH	38.76	21712547
140	Phosphorylation	DRSSQVNTPDLSQRP CCCCCCCCCCHHHCC	21.23	24763107
151	Phosphorylation	SQRPSDDSFLSNEKL HHCCCCCCCCCHHHH	32.83	21712547
183	Phosphorylation	AVDSSSGSPSPPMAL HHCCCCCCCCCCCCC	24.93	25720772
185	Phosphorylation	DSSSGSPSPPMALSQ CCCCCCCCCCCCCCH	43.25	29996109
217	Phosphorylation	EELTKIFSLPTLAPI HHHHHHHCCCCCCCC	36.59	27738172
233	Phosphorylation	GNEEDDASEDAKHSP CCCCCCCCCHHCCCC	42.90	21712547
239	Phosphorylation	ASEDAKHSPKKHSPA CCCHHCCCCCCCCCC	37.39	21712547
244	Phosphorylation	KHSPKKHSPALSDGT CCCCCCCCCCCCCCC	22.28	28889911
248	Phosphorylation	KKHSPALSDGTTSND CCCCCCCCCCCCCCC	35.78	21712547
251	Phosphorylation	SPALSDGTTSNDGAP CCCCCCCCCCCCCCC	31.85	21712547
252	Phosphorylation	PALSDGTTSNDGAPL CCCCCCCCCCCCCCC	30.94	21712547
392	Phosphorylation	RIIYRLNSGEFREVL HHHHHCCCCCHHHHH	44.27	28889911
413	Phosphorylation	LVEDAHIYELLAAAA HHCHHHHHHHHHHHC	7.23	28889911
421	Phosphorylation	ELLAAAASDQVKHLT HHHHHHCCHHCCCHH	24.69	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RBA50_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RBA50_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RBA50_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of RBA50_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.