RAX2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RAX2_SCHPO
• UniProt AC: O14239
• Protein Name: Polarized growth protein rax2
• Gene Name: rax2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1155
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Localizes at the cell cortex of the 'old' growing cell tips.
• Protein Description: Controls cell polarity, through the G1 phase of mitosis, via regulation of for3 localization. Required for actin cable formation where it directs the spatial distribution of the actin cables..
• Protein Sequence: MAIYSSFWIRLYFTFRFFCYFLTSVVASDVSFLGDFSGFNVLSNSSANTDLSSQFFEQTNNGSLSSLIDTSYSNSQICYSSWQGDLYVIVLDSEQQTVLLQSNFTSNPTSLEIFSSQNTSFFGNISAIFCDDKFPYAYATFTFSDKPSFTSIYRWNVTNSNVTIEHFYNVKGNVDSLFFLNNDSVAISGNFTEISPFSSSNGPQIAKLAFRSNNSFSQNSLNRNLSSVSCDLTDSYSLWDPSSSGLVSIYAWAPYLIDFNRIRFYNYESSENSVAFFSAINPADGTVLPLTHYDLETGLSSTCDVNCSLQNFANYQDFYFSKGYNSYQIEIQMFGNGEATENSAFGLSSLQFFETNQNSYFDDSYNQESCGFPGLNSLSSYEGNFEASFSNASMPYWIQTIAGEQASVSFFPNITVPTNGTVQLLIPGCTYDNTCSQRGSVIANVYFAKNKQPATKLVQQASDFDQYVSLYSGYLQGFSDNFRPYVELLPYKNSRMVTHSIRFLEQSYTNVSNGLVFVNTTTDVNKLPSIIEFPAASKLRGTAISQIKSLSNGNFSLYMTGNFSDNYGNNVVYMDSLNHLHSFPNNGLNGWVSYIYVSGDSSYFGGNFTHTGDGSIKLNYIAMYSETSRNWSSLGLGTNGPVTHIGSTSLFIDGKIESFISFQGDFNEVYTSEGYAISTSGFSLWNPSSKSWVSMEKLGFYMSGYLFDIPGFNSTQRIYSGNLSAIASYSTRNIAHFSSDSLNDTFIPCYVNAFPSYIRLEDIAYPFANNSMIAILGSEEMEDKCTAAVYFANSTEPIYPKRILSANCSSKFIVLEDCLIIYSNDTDESDIVKNTFVSFNTTSNSLGNTTALSQLKGHINSVIVDDSYNNIFFGGNLSEQSSGCVGFCIFEYNSSSWRNISHNLISAEVQSILWVNETYSSMYLAGKFVWDTSDVDYLLMYNFDNNTIMSCKGSSSIPGPVLLASLKSQSKDEYSVLLYGTEVSSSDTYLNVLNSEGAINSYSLDIHLNQSTINSIDFFESNQISQIPINDSIIVLSGLIVLDDSSKASAVYCVNKSCLPLLTAFKDNGEAGIVRKVVQQKSFSSSASKMIPVTTKYDHIGQPRYVVIISLGISIGVMFLIMSGSIVVEIIHWFFSEHVETLHDYSNFLKELKTQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
44	N-linked_Glycosylation	SGFNVLSNSSANTDL CCCEECCCCCCCCCH	35.50	-
61	N-linked_Glycosylation	QFFEQTNNGSLSSLI HHHHHCCCCCHHHHE	44.83	-
103	N-linked_Glycosylation	QTVLLQSNFTSNPTS CEEEEECCCCCCCCC	31.11	-
118	N-linked_Glycosylation	LEIFSSQNTSFFGNI EEEEECCCCCCCCCE	39.37	-
124	N-linked_Glycosylation	QNTSFFGNISAIFCD CCCCCCCCEEEEECC	21.64	-
156	N-linked_Glycosylation	FTSIYRWNVTNSNVT CEEEEEEEECCCCEE	23.03	-
161	N-linked_Glycosylation	RWNVTNSNVTIEHFY EEEECCCCEEEEEEE	36.70	-
182	N-linked_Glycosylation	DSLFFLNNDSVAISG CEEEEECCCEEEEEC	45.11	-
190	N-linked_Glycosylation	DSVAISGNFTEISPF CEEEEECCCEEEECC	33.60	-
213	N-linked_Glycosylation	AKLAFRSNNSFSQNS HHHHHHCCCCCCCCC	43.86	-
224	N-linked_Glycosylation	SQNSLNRNLSSVSCD CCCCCCCCCCEEECC	43.11	-
306	N-linked_Glycosylation	LSSTCDVNCSLQNFA CCCCCCCCCEECCCC	9.08	-
391	N-linked_Glycosylation	NFEASFSNASMPYWI CCEECCCCCCCCEEE	33.74	-
413	N-linked_Glycosylation	ASVSFFPNITVPTNG CEEEECCCEECCCCC	37.09	-
419	N-linked_Glycosylation	PNITVPTNGTVQLLI CCEECCCCCEEEEEC	37.76	-
510	N-linked_Glycosylation	FLEQSYTNVSNGLVF HHHHCEEECCCCEEE	27.30	-
519	N-linked_Glycosylation	SNGLVFVNTTTDVNK CCCEEEEECCCCHHH	21.90	-
554	N-linked_Glycosylation	IKSLSNGNFSLYMTG EEECCCCCEEEEEEC	27.81	-
562	N-linked_Glycosylation	FSLYMTGNFSDNYGN EEEEEECCCCCCCCC	24.88	-
607	N-linked_Glycosylation	DSSYFGGNFTHTGDG CCCEECCCCEECCCC	38.74	-
630	N-linked_Glycosylation	MYSETSRNWSSLGLG EEECCCCCHHHCCCC	42.63	-
713	N-linked_Glycosylation	LFDIPGFNSTQRIYS EEECCCCCCCCEEEC	50.49	-
722	N-linked_Glycosylation	TQRIYSGNLSAIASY CCEEECCCHHHEEEE	25.53	-
743	N-linked_Glycosylation	HFSSDSLNDTFIPCY CCCCCCCCCCCEEEE	50.67	-
769	N-linked_Glycosylation	DIAYPFANNSMIAIL HCCCCCCCCCEEEEE	41.30	-
793	N-linked_Glycosylation	TAAVYFANSTEPIYP CEEEEECCCCCCCCC	39.30	-
807	N-linked_Glycosylation	PKRILSANCSSKFIV CHHHEECCCCCCEEE	23.87	-
824	N-linked_Glycosylation	DCLIIYSNDTDESDI CEEEEEECCCCHHHH	38.95	-
840	N-linked_Glycosylation	KNTFVSFNTTSNSLG HCEEEEEECCCCCCC	34.63	-
848	N-linked_Glycosylation	TTSNSLGNTTALSQL CCCCCCCCHHHHHHH	39.28	-
876	N-linked_Glycosylation	NNIFFGGNLSEQSSG CCEEECCCCCCCCCC	40.55	-
893	N-linked_Glycosylation	GFCIFEYNSSSWRNI EEEEEEECCCCCCCC	28.37	-
899	N-linked_Glycosylation	YNSSSWRNISHNLIS ECCCCCCCCCHHHHH	33.58	-
916	N-linked_Glycosylation	VQSILWVNETYSSMY HHHHHEECCCCCCCC	25.06	-
945	N-linked_Glycosylation	LLMYNFDNNTIMSCK EEEEECCCCEEEECC	43.33	-
1009	N-linked_Glycosylation	YSLDIHLNQSTINSI EEEEEEECCCCCCEE	21.42	-
1030	N-linked_Glycosylation	QISQIPINDSIIVLS CCCCCCCCCEEEEEE	31.46	-
1055	N-linked_Glycosylation	ASAVYCVNKSCLPLL CCEEEEECHHHHHHH	27.28	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RAX2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RAX2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RAX2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of RAX2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.