RASA3_RAT - dbPTM
RASA3_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RASA3_RAT
UniProt AC Q9QYJ2
Protein Name Ras GTPase-activating protein 3
Gene Name Rasa3
Organism Rattus norvegicus (Rat).
Sequence Length 834
Subcellular Localization
Protein Description Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) (By similarity)..
Protein Sequence MAVEEEGLRVFQSVRIKIGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLHVLRYASSYEAWYFLQPRDNGSKSVKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFSVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAIGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFIIDDPQETYRTLKQVIAGVGTLEQEHAQYRRNKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAVEEEGLR
------CCCCCCCCE		19.89-
66PhosphorylationPFYGEDFYCEIPRSF
CCCCCCCEEECCCHH		11.07-
77PhosphorylationPRSFRHLSFYIFDRD
CCHHHCEEEEEECCH		15.18-
110PhosphorylationQRYHNRDTWFQLQHV
HHHHCCCCEEEEEEC		25.58-
203PhosphorylationEVFYFEVTRPCSYSK
EEEEEEEECCCCCCC		22.9930181290
207PhosphorylationFEVTRPCSYSKKSHF
EEEECCCCCCCCCCC		34.8130181290
209PhosphorylationVTRPCSYSKKSHFDF
EECCCCCCCCCCCCC		19.8130181290
612PhosphorylationLTNHEFTYQKSKGDQ
HCCCEEEEECCCCCC		21.18-
805PhosphorylationRRNKFKKTRYGSQEH
HHHCCCCCCCCCCCC		29.7022673903
807PhosphorylationNKFKKTRYGSQEHPI
HCCCCCCCCCCCCCC		26.7625575281
809PhosphorylationFKKTRYGSQEHPIGD
CCCCCCCCCCCCCCC		24.3827097102
822PhosphorylationGDKSFQNYIRQQSEI
CCHHHHHHHHHHHCC		6.1622276854
827PhosphorylationQNYIRQQSEISTHSI
HHHHHHHHCCCCCCC		28.6722673903
830PhosphorylationIRQQSEISTHSI---
HHHHHCCCCCCC---		18.9327097102
831PhosphorylationRQQSEISTHSI----
HHHHCCCCCCC----		25.8827097102
833PhosphorylationQSEISTHSI------
HHCCCCCCC------		30.0427097102
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RASA3_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RASA3_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RASA3_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of RASA3_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RASA3_RAT

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Related Literatures of Post-Translational Modification

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