RAMP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RAMP2_HUMAN
• UniProt AC: O60895
• Protein Name: Receptor activity-modifying protein 2
• Gene Name: RAMP2
• Organism: Homo sapiens (Human).
• Sequence Length: 175
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Description: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL..
• Protein Sequence: MASLRVERAGGPRLPRTRVGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
130	N-linked_Glycosylation	THQIHFANCSLVQPT HCCEEECCCCEECCC	18.24	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RAMP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RAMP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RAMP2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RAMP2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.