dbPTM

RABE2_BOVIN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RABE2_BOVIN
UniProt AC	A4FUG8
Protein Name	Rab GTPase-binding effector protein 2
Gene Name	RABEP2
Organism	Bos taurus (Bovine).
Sequence Length	585
Subcellular Localization	Cytoplasm. Early endosome.
Protein Description	Plays a role in membrane trafficking and in homotypic early endosome fusion..
Protein Sequence	MAAAAPAAAGEDGRRRLPGAALDIQPQEGAKVEAESGELERLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSYEAQITSLKQERQQQQQDCEEKERELGRLKQLLSRAHPLDSLEKQMEKAHEDSEKLREIVLPMEQEIEELKAKLLRAEELIQEIQRRPRHPPSLHGSTELLLSRDPSPPLEPLEELSEDGGPAAEAFAHNCDDSASISSFSLGGGASGRASLPRSRQGLSPEQEETASLVSTGTLVPEGIYLPPPGYQLVPDNQWEQLQLEGRQLQKDLESISRERDELQEGLRRSNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQLQMAELANSHKCLSHEVKRLTEENQGLRAEQPSSSVPRVLEQDEGWEESLPSSLPELQQLVRRTQQEARARQQAQEHEAERLRIEIVTLREALDEETAARASLEGQLRVQREETEVLEASLCSLRMEMERVQEEQSKAKRQEVLRPSQGTGRTEEAQLTDLLSEQRAKMLRLQAELETSEQVQRDFVRLSQALQVRLERIRQAGSLEQVRGIIDEAPLRDVRDIKDT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAAAPAAA ------CCCCCCCCC	13.05	-
188	Phosphorylation	RRPRHPPSLHGSTEL HCCCCCCCCCCCHHH	37.13	-
192	Phosphorylation	HPPSLHGSTELLLSR CCCCCCCCHHHHHCC	14.15	-
198	Phosphorylation	GSTELLLSRDPSPPL CCHHHHHCCCCCCCC	34.31	-
202	Phosphorylation	LLLSRDPSPPLEPLE HHHCCCCCCCCCCHH	43.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RABE2_BOVIN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RABE2_BOVIN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RABE2_BOVIN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RABE2_BOVIN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RABE2_BOVIN

Related Literatures of Post-Translational Modification