| UniProt ID | RAB6B_MOUSE | |
|---|---|---|
| UniProt AC | P61294 | |
| Protein Name | Ras-related protein Rab-6B | |
| Gene Name | Rab6b | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 208 | |
| Subcellular Localization |
Golgi apparatus membrane Lipid-anchor . Endoplasmic reticulum-Golgi intermediate compartment . Cytoplasmic vesicle . Colocalizes with BICD1 at vesicular structures that align along microtubules. |
|
| Protein Description | Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (By similarity).. | |
| Protein Sequence | MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSAGGDFGN ------CCCCCCCCC | 35.30 | 26824392 | |
| 15 | Ubiquitination | GNPLRKFKLVFLGEQ CCCCCCEEEEEEECC | 46.94 | 22790023 | |
| 23 | Phosphorylation | LVFLGEQSVGKTSLI EEEEECCCCCCCHHH | 28.65 | 22817900 | |
| 26 | Ubiquitination | LGEQSVGKTSLITRF EECCCCCCCHHHHHH | 32.55 | 22790023 | |
| 54 | Phosphorylation | GIDFLSKTMYLEDRT EEEECCCCCEECCCE | 13.99 | 29899451 | |
| 77 | Phosphorylation | AGQERFRSLIPSYIR CCHHHHHHHCHHHHC | 28.12 | - | |
| 113 | Phosphorylation | KWIDDVRTERGSDVI HHHHHHHHHCCCCEE | 29.86 | 29899451 | |
| 117 | Phosphorylation | DVRTERGSDVIIMLV HHHHHCCCCEEEEEE | 34.62 | 21183079 | |
| 127 | Ubiquitination | IIMLVGNKTDLADKR EEEEECCCCCCCCCC | 37.17 | 22790023 | |
| 133 | Ubiquitination | NKTDLADKRQITIEE CCCCCCCCCCEEHHH | 40.36 | 22790023 | |
| 164 | Ubiquitination | AKTGYNVKQLFRRVA CCCCCCHHHHHHHHH | 37.33 | 22790023 | |
| 172 | Phosphorylation | QLFRRVASALPGMEN HHHHHHHHHCCCCHH | 27.73 | 29899451 | |
| 183 | Ubiquitination | GMENVQEKSKEGMID CCHHHHHHHHCCCEE | 50.14 | 22790023 | |
| 206 | Geranylgeranylation | PPASEGGCSC----- CCCCCCCCCC----- | 5.73 | - | |
| 208 | Methylation | ASEGGCSC------- CCCCCCCC------- | 8.22 | - | |
| 208 | Geranylgeranylation | ASEGGCSC------- CCCCCCCC------- | 8.22 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RAB6B_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RAB6B_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RAB6B_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RAB6B_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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