dbPTM

RAB4A_BOVIN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RAB4A_BOVIN
UniProt AC	Q2TBH7
Protein Name	Ras-related protein Rab-4A
Gene Name	RAB4A
Organism	Bos taurus (Bovine).
Sequence Length	218
Subcellular Localization	Membrane Peripheral membrane protein . Cytoplasm . Early endosome membrane Peripheral membrane protein . Recycling endosome membrane Peripheral membrane protein . Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
Protein Description	Protein transport. Probably involved in vesicular traffic (By similarity)..
Protein Sequence	MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDTDREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPSAQECGC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Serotonylation	QIWDTAGQERFRSVT EEEECCCHHHHHHHH	25.73	-
190	Phosphorylation	LDPERMGSGIQYGDA CCHHHCCCCCCHHHH	11.16	-
204	Phosphorylation	AALRQLRSPRRAQAP HHHHHCCCCCHHCCC	52.58	-
216	Geranylgeranylation	QAPSAQECGC----- CCCCHHHCCC-----		-
218	Methylation	PSAQECGC------- CCHHHCCC-------		-
218	Geranylgeranylation	PSAQECGC------- CCHHHCCC-------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
204	S	Phosphorylation	Kinase	CDK1	P48734	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RAB4A_BOVIN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RAB4A_BOVIN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RAB4A_BOVIN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RAB4A_BOVIN

Related Literatures of Post-Translational Modification