RAB2A_MOUSE - dbPTM
RAB2A_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RAB2A_MOUSE
UniProt AC P53994
Protein Name Ras-related protein Rab-2A
Gene Name Rab2a
Organism Mus musculus (Mouse).
Sequence Length 212
Subcellular Localization Endoplasmic reticulum-Golgi intermediate compartment membrane
Lipid-anchor. Melanosome. Endoplasmic reticulum membrane
Lipid-anchor . Golgi apparatus membrane
Lipid-anchor .
Protein Description Required for protein transport from the endoplasmic reticulum to the Golgi complex..
Protein Sequence MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHGSNQGGQQAGGGCC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAYAYLFKY
------CCHHEEEEE		9.54-
3Phosphorylation-----MAYAYLFKYI
-----CCHHEEEEEE		8.4222499769
5Phosphorylation---MAYAYLFKYIII
---CCHHEEEEEEEE		10.4528066266
15PhosphorylationKYIIIGDTGVGKSCL
EEEEECCCCCCHHHE		28.6722817900
21S-nitrosocysteineDTGVGKSCLLLQFTD
CCCCCHHHEEEEEEC		3.37-
21S-nitrosylationDTGVGKSCLLLQFTD
CCCCCHHHEEEEEEC		3.3720925432
29AcetylationLLLQFTDKRFQPVHD
EEEEEECCCCCCCCE		52.6422826441
29UbiquitinationLLLQFTDKRFQPVHD
EEEEEECCCCCCCCE		52.6422790023
53AcetylationRMITIDGKQIKLQIW
EEEEECCEEEEEEEE		45.1422826441
56UbiquitinationTIDGKQIKLQIWDTA
EECCEEEEEEEEECC		31.6722790023
62PhosphorylationIKLQIWDTAGQESFR
EEEEEEECCCHHHHH		20.0728066266
67PhosphorylationWDTAGQESFRSITRS
EECCCHHHHHHHHHH		20.3325159016
70PhosphorylationAGQESFRSITRSYYR
CCHHHHHHHHHHHHC		26.7123984901
72PhosphorylationQESFRSITRSYYRGA
HHHHHHHHHHHHCCC		18.1423984901
74PhosphorylationSFRSITRSYYRGAAG
HHHHHHHHHHCCCCC		20.1923140645
75PhosphorylationFRSITRSYYRGAAGA
HHHHHHHHHCCCCCE		8.2229514104
76PhosphorylationRSITRSYYRGAAGAL
HHHHHHHHCCCCCEE		12.1023140645
86PhosphorylationAAGALLVYDITRRDT
CCCEEEEEECCCCHH		11.1223140645
89PhosphorylationALLVYDITRRDTFNH
EEEEEECCCCHHHHH		19.4323140645
108PhosphorylationLEDARQHSNSNMVIM
HHHHHHHCCCCEEEE		33.3525521595
110PhosphorylationDARQHSNSNMVIMLI
HHHHHCCCCEEEEEE		29.3529899451
120UbiquitinationVIMLIGNKSDLESRR
EEEEECCHHHHHHHH		39.8822790023
130UbiquitinationLESRREVKKEEGEAF
HHHHHHHHHHHHHHH		50.1122790023
154PhosphorylationETSAKTASNVEEAFI
ECCCCCCCCHHHHHH		46.7929899451
165UbiquitinationEAFINTAKEIYEKIQ
HHHHHHHHHHHHHHH		42.4822790023
168PhosphorylationINTAKEIYEKIQEGV
HHHHHHHHHHHHHCC		16.56-
170UbiquitinationTAKEIYEKIQEGVFD
HHHHHHHHHHHCCCC		32.4922790023
211GeranylgeranylationGQQAGGGCC------
CCCCCCCCC------		2.55-
212GeranylgeranylationQQAGGGCC-------
CCCCCCCC-------		7.65-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RAB2A_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RAB2A_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RAB2A_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of RAB2A_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RAB2A_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory