R3HD4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: R3HD4_HUMAN
• UniProt AC: Q96D70
• Protein Name: R3H domain-containing protein 4
• Gene Name: R3HDM4
• Organism: Homo sapiens (Human).
• Sequence Length: 268
• Subcellular Localization: Nucleus .
• Protein Sequence: MVALENPECGPEAAEGTPGGRRLLPLPSCLPALASSQVKRLSASRRKQHFINQAVRNSDLVPKAKGRKSLQRLENTQYLLTLLETDGGLPGLEDGDLAPPASPGIFAEACNNATYVEVWNDFMNRSGEEQERVLRYLEDEGRSKARRRGPGRGEDRRREDPAYTPRECFQRISRRLRAVLKRSRIPMETLETWEERLLRFFSVSPQAVYTAMLDNSFERLLLHAVCQYMDLISASADLEGKRQMKVSNRHLDFLPPGLLLSAYLEQHS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	GPEAAEGTPGGRRLL CHHHCCCCCCCCCCC	15.40	21815630
35	Phosphorylation	SCLPALASSQVKRLS CHHHHHHHHHHHHHC	23.35	29214152
36	Phosphorylation	CLPALASSQVKRLSA HHHHHHHHHHHHHCH	33.13	21712546
39	Ubiquitination	ALASSQVKRLSASRR HHHHHHHHHHCHHHH	39.73	-
47	Ubiquitination	RLSASRRKQHFINQA HHCHHHHHHHHHHHH	47.19	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of R3HD4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of R3HD4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of R3HD4_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of R3HD4_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.