R10B1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: R10B1_HUMAN
• UniProt AC: P0C881
• Protein Name: Radial spoke head 10 homolog B
• Gene Name: RSPH10B
• Organism: Homo sapiens (Human).
• Sequence Length: 870
• Protein Sequence: MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKDRQNVQQNEDATQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVAPRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITELRRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEEIHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNAFQIKGNLFREQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATFMEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNMYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADVSSSHLILDPPKEDVTVSPSSKTITSKKKKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	ADKKGEKSARSPSSL CCCCCCCCCCCCCCC	25.31	26074081
18	Phosphorylation	KGEKSARSPSSLSDN CCCCCCCCCCCCCCC	28.93	26074081
20	Phosphorylation	EKSARSPSSLSDNLD CCCCCCCCCCCCCCC	45.20	26074081
21	Phosphorylation	KSARSPSSLSDNLDF CCCCCCCCCCCCCCC	34.96	26074081
23	Phosphorylation	ARSPSSLSDNLDFSK CCCCCCCCCCCCCCC	26.80	22210691
29	Phosphorylation	LSDNLDFSKQDGNTT CCCCCCCCCCCCCCC	29.13	22210691
35	Phosphorylation	FSKQDGNTTRQEMSP CCCCCCCCCCHHCCC	28.96	26074081
36	Phosphorylation	SKQDGNTTRQEMSPA CCCCCCCCCHHCCCC	34.06	26074081
41	Phosphorylation	NTTRQEMSPAGVPLL CCCCHHCCCCCCCCC	15.73	22210691
76	Phosphorylation	DATQYEESILTKLIV CHHHHHHHHHHHHHH	15.80	24719451
275	Phosphorylation	WFLKRIRSSQYPLRN HHHHHHHHCCCCCCC	21.30	23403867
276	Phosphorylation	FLKRIRSSQYPLRNE HHHHHHHCCCCCCCC	24.72	-
292	Phosphorylation	IGEFVNGYRHGRGKF CHHHCCCCCCCCCEE	8.34	29759185
364	Phosphorylation	SGVAPRLSRSAELIR CCCCCCHHHHHHHHH	26.01	30622161
366	Phosphorylation	VAPRLSRSAELIRKL CCCCHHHHHHHHHHH	23.79	30622161
435	Phosphorylation	SSLGCGHSLDNTFLM HHCCCCCCCCCCHHH	23.78	-
439	Phosphorylation	CGHSLDNTFLMTKLH CCCCCCCCHHHHHHH	20.15	-
471	Phosphorylation	ADMDRILSANNDIPV HHHHHHHHCCCCCCH	26.95	-
521	Phosphorylation	PSLFLCFTKLMTENI HHHHHHHHHHHHCCC	23.44	30631047
634	Phosphorylation	EFFEALLSFAFICVT HHHHHHHHHHHHHCH	18.51	-
641	Phosphorylation	SFAFICVTDQMTKSY HHHHHHCHHHCCCCC	18.99	-
645	Phosphorylation	ICVTDQMTKSYTNVP HHCHHHCCCCCCCCC	15.94	-
703	Phosphorylation	SSSKLELSPDVNKIR CCCCCCCCCCHHHHH	15.07	19664994
841	Phosphorylation	LKEPADVSSSHLILD ECCCCCCCCCCEEEC	27.03	25693802
842	Phosphorylation	KEPADVSSSHLILDP CCCCCCCCCCEEECC	22.94	25693802
843	Phosphorylation	EPADVSSSHLILDPP CCCCCCCCCEEECCC	18.14	25693802
857	Phosphorylation	PKEDVTVSPSSKTIT CCCCCEECCCCCCCC	15.08	-
860	Phosphorylation	DVTVSPSSKTITSKK CCEECCCCCCCCCCC	36.88	-
862	Phosphorylation	TVSPSSKTITSKKKK EECCCCCCCCCCCCC	31.28	-
864	O-linked_Glycosylation	SPSSKTITSKKKKK- CCCCCCCCCCCCCC-	39.46	30379171
864	Phosphorylation	SPSSKTITSKKKKK- CCCCCCCCCCCCCC-	39.46	-
865	Phosphorylation	PSSKTITSKKKKK-- CCCCCCCCCCCCC--	38.33	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of R10B1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of R10B1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of R10B1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of R10B1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.