QRIC2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: QRIC2_HUMAN
• UniProt AC: Q9H0J4
• Protein Name: Glutamine-rich protein 2
• Gene Name: QRICH2
• Organism: Homo sapiens (Human).
• Sequence Length: 1663
• Protein Sequence: MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTMVTWEELEQAITDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQPSIEQALDSASGLGPDRTASGSGGTAHPSDGVSSREQSKVPSGTGRQQQPRARDEAGVPRLHQSSTFQFKSDSDRHRSREKLTSTQPRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGLPGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHSKMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYSTVPRRCGGSHTLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILRKDSSGTSKRKSQQPRPHVHRPPSLSSNGQLPSRPQSAQISAGNTSER

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	KDAAEELSFARVLLQ HHHHHHHHHHHHHHH	21.82	25599653
67	Phosphorylation	ITDGWRASQAGSETL HHHCHHHHHCCCCCE	16.40	25693802
71	Phosphorylation	WRASQAGSETLMGFS HHHHHCCCCCEECEE	30.35	30622161
73	Phosphorylation	ASQAGSETLMGFSKH HHHCCCCCEECEECC	24.60	30622161
78	Phosphorylation	SETLMGFSKHGGFTS CCCEECEECCCCCCC	20.29	30622161
142	Phosphorylation	REQSKVPSGTGRQQQ CCCCCCCCCCCCCCC	52.56	24719451
624	Phosphorylation	QPGEVQRSLVQPGIV CCCCHHHHHCCCCCC	18.79	-
857	Phosphorylation	REQYGQVSPLLASQG HHHHCCCHHHHHHCC	11.27	25693802
862	Phosphorylation	QVSPLLASQGLASPG CCHHHHHHCCCCCCC	25.42	25693802
867	Phosphorylation	LASQGLASPGIDRRS HHHCCCCCCCCCHHH	28.80	25693802
987	Phosphorylation	KAPGQDVTLFRSPDS CCCCCCEEEEECCHH	28.59	30622161
991	Phosphorylation	QDVTLFRSPDSVDRV CCEEEEECCHHHHHH	26.23	30622161
994	Phosphorylation	TLFRSPDSVDRVLSE EEEECCHHHHHHHHC	29.33	30622161
1000	Phosphorylation	DSVDRVLSEGSEVSS HHHHHHHHCCCCHHH	36.73	25693802
1003	Phosphorylation	DRVLSEGSEVSSEVL HHHHHCCCCHHHHHH	30.67	25693802
1006	Phosphorylation	LSEGSEVSSEVLSER HHCCCCHHHHHHHHH	19.41	30622161
1007	Phosphorylation	SEGSEVSSEVLSERR HCCCCHHHHHHHHHH	36.58	30622161
1265	Phosphorylation	ELLGRVQSAILQVQG HHHHHHHHHHHHHHC	17.89	30622161
1299	Phosphorylation	QKDIAMLYQGLEKLE HHHHHHHHHHHHHHH	6.35	28842319
1497	Phosphorylation	QSVGRLRSMHSKMLM HHHHHHHHHHHHHCC	25.99	30206219
1500	Phosphorylation	GRLRSMHSKMLMNIE HHHHHHHHHHCCCEE	15.89	30206219
1508	Acetylation	KMLMNIEKVQIHFGG HHCCCEEEEEEECCC	35.33	7963415
1518	Acetylation	IHFGGSTKASSQIIR EECCCCHHHHHHHHH	48.22	7963425
1521	Phosphorylation	GGSTKASSQIIRELL CCCHHHHHHHHHHHH	30.20	24275569
1538	Phosphorylation	QCLGSPCYKRVTDMA HHHCCCHHHHHCCCC	12.76	24114839
1542	Phosphorylation	SPCYKRVTDMADYTY CCHHHHHCCCCCCCC	24.88	-
1549	Phosphorylation	TDMADYTYSTVPRRC CCCCCCCCCCCCCCC	8.98	-
1627	Phosphorylation	SGTSKRKSQQPRPHV CCCCCCCCCCCCCCC	37.77	25599653
1639	Phosphorylation	PHVHRPPSLSSNGQL CCCCCCCCCCCCCCC	43.49	27174698
1641	Phosphorylation	VHRPPSLSSNGQLPS CCCCCCCCCCCCCCC	26.54	27174698
1642	Phosphorylation	HRPPSLSSNGQLPSR CCCCCCCCCCCCCCC	50.72	27174698
1648	Phosphorylation	SSNGQLPSRPQSAQI CCCCCCCCCCCCCCC	66.25	27174698
1652	Phosphorylation	QLPSRPQSAQISAGN CCCCCCCCCCCCCCC	25.48	30631047
1661	Phosphorylation	QISAGNTSER----- CCCCCCCCCC-----	35.06	30631047

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of QRIC2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of QRIC2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of QRIC2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of QRIC2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.