QCR8_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: QCR8_MOUSE
• UniProt AC: Q9CQ69
• Protein Name: Cytochrome b-c1 complex subunit 8
• Gene Name: Uqcrq
• Organism: Mus musculus (Mouse).
• Sequence Length: 82
• Subcellular Localization: Mitochondrion inner membrane.
• Protein Description: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone..
• Protein Sequence: MGREFGNLARIRHVISYSLSPFEQRAFPSYFSKGIPNVLRRTRERILRVAPPFVVVYLIYTWGNQEFEQSKRKNPAMYENDK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	ARIRHVISYSLSPFE HHHHHHHHEECCHHH	13.95	-
29	Phosphorylation	FEQRAFPSYFSKGIP HHHHHCHHHHCCCHH	32.15	23737553
30	Phosphorylation	EQRAFPSYFSKGIPN HHHHCHHHHCCCHHH	16.47	29472430
32	Phosphorylation	RAFPSYFSKGIPNVL HHCHHHHCCCHHHHH	23.03	29472430
33	Acetylation	AFPSYFSKGIPNVLR HCHHHHCCCHHHHHH	51.46	23576753
33	Succinylation	AFPSYFSKGIPNVLR HCHHHHCCCHHHHHH	51.46	-
33	Ubiquitination	AFPSYFSKGIPNVLR HCHHHHCCCHHHHHH	51.46	-
33	Succinylation	AFPSYFSKGIPNVLR HCHHHHCCCHHHHHH	51.46	23806337
82	Acetylation	PAMYENDK------- HHHHCCCC-------	74.04	23864654

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of QCR8_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of QCR8_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of QCR8_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of QCR8_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Ubiquitylation

"A proteomics approach to identify the ubiquitinated proteins in mouseheart.";
Jeon H.B., Choi E.S., Yoon J.H., Hwang J.H., Chang J.W., Lee E.K.,Choi H.W., Park Z.-Y., Yoo Y.J.;
Biochem. Biophys. Res. Commun. 357:731-736(2007).
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-33, AND MASSSPECTROMETRY.
PubMed: 17451654