PYRC_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PYRC_ARATH
• UniProt AC: O04904
• Protein Name: Dihydroorotase, mitochondrial
• Gene Name: PYR4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 377
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MIKTLVSPYSGFGSQKLKFDRSSEKVKTRAVRMELTITQPDDWHLHLRDGDLLHAVVPHSASNFKRAIVMPNLKPPVTSTAAAIIYRKFIMKALPSESSFDPLMTLYLTDKTLPEEIRLARESGVVYAVKLYPAGATTNSQDGVTDLFGKCLPVLEEMVKQNMPLLVHGEVTDPSIDVFDREKIFIETVLQPLIQRLPQLKVVMEHITTMDAVNFVESCKEGSVGATVTPQHLLLNRNALFQGGLQPHNYCLPVLKREIHREAIVKAVTSGSKKFFLGTDSAPHERSRKESSCGCAGIYSAPIALSLYAKVFDEAGALDKLEAFTSFNGPDFYGLPRNSSKITLKKSPWKVPDVFNFPFGEIVPMFAGETLQWQPLK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
130	N6-carboxylysine	SGVVYAVKLYPAGAT HCCEEEEEEEECCCC	33.85	-
130	Carboxylation	SGVVYAVKLYPAGAT HCCEEEEEEEECCCC	33.85	-
223	Phosphorylation	VESCKEGSVGATVTP HHHCCCCCCCCEECH	20.61	22092075

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PYRC_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PYRC_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PYRC_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PYRC_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.