PXDC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PXDC1_HUMAN
• UniProt AC: Q5TGL8
• Protein Name: PX domain-containing protein 1
• Gene Name: PXDC1
• Organism: Homo sapiens (Human).
• Sequence Length: 231
• Protein Sequence: MASAVFEGTSLVNMFVRGCWVNGIRRLIVSRRGDEEEFFEIRTEWSDRSVLYLHRSLADLGRLWQRLRDAFPEDRSELAQGPLRQGLVAIKEAHDIETRLNEVEKLLKTIISMPCKYSRSEVVLTFFERSPLDQVLKNDNVHKIQPSFQSPVKISEIMRSNGFCLANTETIVIDHSIPNGRDQQLGVDPTEHLFENGSEFPSELEDGDDPAAYVTNLSYYHLVPFETDIWD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASAVFEGTS -----CCCCCCCCHH	24.54	27251275
30	Phosphorylation	GIRRLIVSRRGDEEE HHHHHHCCCCCCHHH	14.85	24719451
108	Acetylation	NEVEKLLKTIISMPC HHHHHHHHHHHHCCC	48.38	7677751
143	Ubiquitination	LKNDNVHKIQPSFQS HHCCCCCCCCCCCCC	38.46	29967540
147	Phosphorylation	NVHKIQPSFQSPVKI CCCCCCCCCCCCEEH	21.39	29396449
150	Phosphorylation	KIQPSFQSPVKISEI CCCCCCCCCEEHHHH	29.65	29255136

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PXDC1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PXDC1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PXDC1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PXDC1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.