dbPTM

PX11B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PX11B_MOUSE
UniProt AC	Q9Z210
Protein Name	Peroxisomal membrane protein 11B
Gene Name	Pex11b
Organism	Mus musculus (Mouse).
Sequence Length	259
Subcellular Localization	Peroxisome membrane Single-pass membrane protein .
Protein Description	Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface..
Protein Sequence	MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLEGHLSLGRKLLRLGNSTDALESAKRAVHLSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQETSAYSRRMKVSGVGVSGGVETVGPGGPGTPGGSLPQLALKFRLRILLLARVLRGHPPLLLDVLRNACDLFIPLDKLGLWRCGPGIVGLCGLISSILSILTLICPWLRLKP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Acetylation	GASPELQKQIRQLEG CCCHHHHHHHHHHHH	61.39	23201123
43	Ubiquitination	GASPELQKQIRQLEG CCCHHHHHHHHHHHH	61.39	22790023
53	Phosphorylation	RQLEGHLSLGRKLLR HHHHHHHHHHHHHHH	24.09	23140645
107	Succinylation	DNVLWAGKSGLAPRV CCEECCCCCCCCCCC	33.34	24315375
151	Phosphorylation	LLMEQETSAYSRRMK HHHHHCCCHHHCCCC	25.18	-
224	Ubiquitination	DLFIPLDKLGLWRCG CCEEEHHHHCCCCCC	52.73	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PX11B_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PX11B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PX11B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PX11B_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PX11B_MOUSE

Related Literatures of Post-Translational Modification