PWD_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PWD_ARATH
• UniProt AC: Q6ZY51
• Protein Name: Phosphoglucan, water dikinase, chloroplastic
• Gene Name: GWD3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1196
• Subcellular Localization: Plastid, chloroplast . Starch granules during starch mobilization in darkness.
• Protein Description: Mediates the incorporation of phosphate into starch-like phospho-alpha-glucan, mostly at the C-3 position of glucose units. Required for starch degradation, suggesting that the phosphate content of starch regulates its degradability..
• Protein Sequence: MESIGSHCCSSPFTFITRNSSSSLPRLVNITHRVNLSHQSHRLRNSNSRLTCTATSSSTIEEQRKKKDGSGTKVRLNVRLDHQVNFGDHVAMFGSAKEIGSWKKKSPLNWSENGWVCELELDGGQVLEYKFVIVKNDGSLSWESGDNRVLKVPNSGNFSVVCHWDATRETLDLPQEVGNDDDVGDGGHERDNHDVGDDRVVGSENGAQLQKSTLGGQWQGKDASFMRSNDHGNREVGRNWDTSGLEGTALKMVEGDRNSKNWWRKLEMVREVIVGSVEREERLKALIYSAIYLKWINTGQIPCFEDGGHHRPNRHAEISRLIFRELEHICSKKDATPEEVLVARKIHPCLPSFKAEFTAAVPLTRIRDIAHRNDIPHDLKQEIKHTIQNKLHRNAGPEDLIATEAMLQRITETPGKYSGDFVEQFKIFHNELKDFFNAGSLTEQLDSMKISMDDRGLSALNLFFECKKRLDTSGESSNVLELIKTMHSLASLRETIIKELNSGLRNDAPDTAIAMRQKWRLCEIGLEDYFFVLLSRFLNALETMGGADQLAKDVGSRNVASWNDPLDALVLGVHQVGLSGWKQEECLAIGNELLAWRERDLLEKEGEEDGKTIWAMRLKATLDRARRLTAEYSDLLLQIFPPNVEILGKALGIPENSVKTYTEAEIRAGIIFQISKLCTVLLKAVRNSLGSEGWDVVVPGSTSGTLVQVESIVPGSLPATSGGPIILLVNKADGDEEVSAANGNIAGVMLLQELPHLSHLGVRARQEKIVFVTCDDDDKVADIRRLVGKFVRLEASPSHVNLILSTEGRSRTSKSSATKKTDKNSLSKKKTDKKSLSIDDEESKPGSSSSNSLLYSSKDIPSGGIIALADADVPTSGSKSAACGLLASLAEASSKVHSEHGVPASFKVPTGVVIPFGSMELALKQNNSEEKFASLLEKLETARPEGGELDDICDQIHEVMKTLQVPKETINSISKAFLKDARLIVRSSANVEDLAGMSAAGLYESIPNVSPSDPLVFSDSVCQVWASLYTRRAVLSRRAAGVSQREASMAVLVQEMLSPDLSFVLHTVSPADPDSNLVEAEIAPGLGETLASGTRGTPWRLASGKLDGIVQTLAFANFSEELLVSGTGPADGKYVRLTVDYSKKRLTVDSVFRQQLGQRLGSVGFFLERNFGCAQDVEGCLVGEDVYIVQSRPQPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	RNSNSRLTCTATSSS CCCCCCEEEEEECCC	13.50	28295753
53	Phosphorylation	SNSRLTCTATSSSTI CCCCEEEEEECCCHH	27.95	28295753
55	Acetylation	SRLTCTATSSSTIEE CCEEEEEECCCHHHH	15.81	22223895
55	Phosphorylation	SRLTCTATSSSTIEE CCEEEEEECCCHHHH	15.81	28295753
56	Phosphorylation	RLTCTATSSSTIEEQ CEEEEEECCCHHHHH	21.59	28295753
57	Phosphorylation	LTCTATSSSTIEEQR EEEEEECCCHHHHHH	27.44	28295753
58	Phosphorylation	TCTATSSSTIEEQRK EEEEECCCHHHHHHH	32.92	28295753
59	Phosphorylation	CTATSSSTIEEQRKK EEEECCCHHHHHHHH	34.06	28295753
242	Phosphorylation	EVGRNWDTSGLEGTA CCCCCCCCCCCCCCE	19.13	28295753
243	Phosphorylation	VGRNWDTSGLEGTAL CCCCCCCCCCCCCEE	38.62	28295753
248	Phosphorylation	DTSGLEGTALKMVEG CCCCCCCCEEEEECC	21.31	28295753
796	Phosphorylation	KFVRLEASPSHVNLI CCEEEECCHHHEEEE	19.98	25561503
798	Phosphorylation	VRLEASPSHVNLILS EEEECCHHHEEEEEE	37.26	30291188
805	Phosphorylation	SHVNLILSTEGRSRT HHEEEEEECCCCCCC	19.88	25561503
806	Phosphorylation	HVNLILSTEGRSRTS HEEEEEECCCCCCCC	38.73	30291188
818	Phosphorylation	RTSKSSATKKTDKNS CCCCCCCCCCCCCCC	34.71	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PWD_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PWD_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PWD_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PWD_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.