PUR2_MOUSE - dbPTM
PUR2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PUR2_MOUSE
UniProt AC Q64737
Protein Name Trifunctional purine biosynthetic protein adenosine-3
Gene Name Gart
Organism Mus musculus (Mouse).
Sequence Length 1010
Subcellular Localization
Protein Description
Protein Sequence MAARVLVIGSGGREHTLAWKLAQSPQVKQVLVAPGNAGTACAGKISNAAVSVNDHSALAQFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHEIPTAQWRAFTNPEDACSFITSANFPALVVKASGLAAGKGVIVAKSQAEACRAVQEIMQEKSFGAAGETVVVEEFLEGEEVSCLCFTDGKTVAEMPPAQDHKRLLDGDEGPNTGGMGAYCPAPQVSKDLLVKIKNTILQRAVDGMQQEGAPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVMQSTLDGLLSASLPVWLENHSAVTVVMASKGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDGKVVTSGGRVLTVTAVQENLMSALAEARKGLAALKFEGAIYRKDIGFRAVAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVIAGIAAACQQAGCALLGGETAEMPNMYPPGEYDLAGFAVGAMERHQKLPQLERITEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSGRVKAFAHITGGGLLENIPRVLPQKFGVDLDASTWRVPKVFSWLQQEGELSEEEMARTFNCGIGAALVVSKDQAEQVLHDVRRRQEEAWVIGSVVACPEDSPRVRVKNLIETIQTNGSLVANGFLKSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAALQLVASGAVQLREDGKIHWAKEQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAARVLVIG
------CCEEEEEEC		18.45-
10PhosphorylationARVLVIGSGGREHTL
EEEEEECCCCHHHHH		27.2729472430
51PhosphorylationKISNAAVSVNDHSAL
CCCCCEEECCCHHHH		15.5228464351
93S-nitrosocysteineLTSAGVRCFGPTAQA
HHHCCCCEECCHHHH		4.26-
93S-nitrosylationLTSAGVRCFGPTAQA
HHHCCCCEECCHHHH		4.2621278135
134S-nitrosocysteineFTNPEDACSFITSAN
CCCHHHHHHHHHCCC		5.44-
134S-nitrosylationFTNPEDACSFITSAN
CCCHHHHHHHHHCCC		5.4421278135
134GlutathionylationFTNPEDACSFITSAN
CCCHHHHHHHHHCCC		5.4424333276
150PhosphorylationPALVVKASGLAAGKG
CEEEEEHHCCCCCCC		28.7324759943
156SuccinylationASGLAAGKGVIVAKS
HHCCCCCCCEEEECH		45.3223806337
156MalonylationASGLAAGKGVIVAKS
HHCCCCCCCEEEECH		45.3226320211
156AcetylationASGLAAGKGVIVAKS
HHCCCCCCCEEEECH		45.3223806337
237S-nitrosylationTGGMGAYCPAPQVSK
CCCCCCCCCCCCCCH		1.9921278135
237S-nitrosocysteineTGGMGAYCPAPQVSK
CCCCCCCCCCCCCCH		1.99-
249AcetylationVSKDLLVKIKNTILQ
CCHHHHHHHHHHHHH		48.1823576753
285UbiquitinationMLTKDGPKVLEFNCR
EEECCCCEEEEEECC		66.0522790023
298S-nitrosylationCRFGDPECQVILPLL
CCCCCCCCCHHHHHH		4.8221278135
298S-nitrosocysteineCRFGDPECQVILPLL
CCCCCCCCCHHHHHH		4.82-
348PhosphorylationSKGYPGAYTKGVEIT
CCCCCCCCCCCEEEC		18.2025367039
349PhosphorylationKGYPGAYTKGVEITG
CCCCCCCCCCEEECC		22.31-
350AcetylationGYPGAYTKGVEITGF
CCCCCCCCCEEECCC		48.56-
398PhosphorylationAVQENLMSALAEARK
HHHHHHHHHHHHHHH		24.25-
436PhosphorylationLQRPRGLTYKDSGVD
CCCCCCCCCCCCCCE		31.2025338131
438UbiquitinationRPRGLTYKDSGVDIA
CCCCCCCCCCCCEEC		39.9322790023
440PhosphorylationRGLTYKDSGVDIAAG
CCCCCCCCCCEECCC		36.2425266776
452UbiquitinationAAGNMLVKKIQPLAK
CCCCCHHHHHHHHHH		39.9522790023
459UbiquitinationKKIQPLAKATSRPGC
HHHHHHHHHCCCCCC		60.9422790023
461PhosphorylationIQPLAKATSRPGCSV
HHHHHHHCCCCCCEE		25.2723984901
462PhosphorylationQPLAKATSRPGCSVD
HHHHHHCCCCCCEEE		41.1423984901
466GlutathionylationKATSRPGCSVDLGGF
HHCCCCCCEEECCCC		3.8724333276
467PhosphorylationATSRPGCSVDLGGFA
HCCCCCCEEECCCCC		25.2821082442
485UbiquitinationDLKAAGFKDPLLASG
CHHHCCCCCCCCCCC		58.4822790023
485AcetylationDLKAAGFKDPLLASG
CHHHCCCCCCCCCCC		58.4822826441
498PhosphorylationSGTDGVGTKLKIAQL
CCCCCCCHHHHHHHH		30.6922210690
657PhosphorylationTLGDLLLTPTRIYSH
CHHHHHCCCCEECCC		23.6822006019
682PhosphorylationVKAFAHITGGGLLEN
EEEEEEECCCHHHHC		21.6526745281
697UbiquitinationIPRVLPQKFGVDLDA
CCCCCCHHCCCCCCC		41.9922790023
798UbiquitinationLVANGFLKSNFPVQQ
EEECCHHHCCCCCCC		40.88-
806UbiquitinationSNFPVQQKKARVAVL
CCCCCCCCCEEEEEE		31.1727667366
866UbiquitinationPTRVINHKLYKNRVE
CHHHCCCHHHCCCCC		49.3622790023
921PhosphorylationIHPSLLPSFKGSNAH
CCHHHCCCCCCCCHH		39.2921454597
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PUR2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PUR2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PUR2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PUR2_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PUR2_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory