PUB44_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PUB44_ARATH
• UniProt AC: Q9LM76
• Protein Name: U-box domain-containing protein 44
• Gene Name: PUB44
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 801
• Protein Description: Functions as an E3 ubiquitin-protein ligase. Prevents premature senescence probably by targeting proteins involved in this process for degradation. Promotes the degradation of AAO3 and thus represses abscisic acid (ABA) biosynthesis..
• Protein Sequence: MVGSSDGDQSDDSSHFERGVDHIYEAFICPLTKEVMHDPVTLENGRTFEREAIEKWFKECRDSGRPPSCPLTSQELTSTDVSASIALRNTIEEWRSRNDAAKLDIARQSLFLGNAETDILQALMHVRQICRTIRSNRHGVRNSQLIHMIIDMLKSTSHRVRYKALQTLQVVVEGDDESKAIVAEGDTVRTLVKFLSHEPSKGREAAVSLLFELSKSEALCEKIGSIHGALILLVGLTSSNSENVSIVEKADRTLENMERSEEIVRQMASYGRLQPLLGKLLEGSPETKLSMASFLGELPLNNDVKVLVAQTVGSSLVDLMRSGDMPQREAALKALNKISSFEGSAKVLISKGILPPLIKDLFYVGPNNLPIRLKEVSATILANIVNIGYDFDKATLVSENRVENLLHLISNTGPAIQCKLLEVLVGLTSCPKTVPKVVYAIKTSGAIISLVQFIEVRENDDLRLASIKLLHNLSPFMSEELAKALCGTAGQLGSLVAIISEKTPITEEQAAAAGLLAELPDRDLGLTQEMLEVGAFEKIISKVFGIRQGDIKGMRFVNPFLEGLVRILARITFVFNKEARAINFCREHDVASLFLHLLQSNGQDNIQMVSAMALENLSLESIKLTRMPDPPPVNYCGSIFSCVRKPHVVNGLCKIHQGICSLRETFCLVEGGAVEKLVALLDHENVKVVEAALAALSSLLEDGLDVEKGVKILDEADGIRHILNVLRENRTERLTRRAVWMVERILRIEDIAREVAEEQSLSAALVDAFQNADFRTRQIAENALKHIDKIPNFSSIFPNIA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MVGSSDGDQSD ----CCCCCCCCCCC	17.53	30407730
5	Phosphorylation	---MVGSSDGDQSDD ---CCCCCCCCCCCC	39.42	30407730
10	Phosphorylation	GSSDGDQSDDSSHFE CCCCCCCCCCCCHHH	48.39	30407730
13	Phosphorylation	DGDQSDDSSHFERGV CCCCCCCCCHHHHHH	30.61	30407730
14	Phosphorylation	GDQSDDSSHFERGVD CCCCCCCCHHHHHHH	38.91	25561503
776	Phosphorylation	FQNADFRTRQIAENA HHCCCHHHHHHHHHH	27.24	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PUB44_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PUB44_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PUB44_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.