PTER_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PTER_HUMAN
• UniProt AC: Q96BW5
• Protein Name: Phosphotriesterase-related protein
• Gene Name: PTER
• Organism: Homo sapiens (Human).
• Sequence Length: 349
• Protein Sequence: MSSLSGKVQTVLGLVEPSKLGRTLTHEHLAMTFDCCYCPPPPCQEAISKEPIVMKNLYWIQKNAYSHKENLQLNQETEAIKEELLYFKANGGGALVENTTTGISRDTQTLKRLAEETGVHIISGAGFYVDATHSSETRAMSVEQLTDVLMNEILHGADGTSIKCGIIGEIGCSWPLTESERKVLQATAHAQAQLGCPVIIHPGRSSRAPFQIIRILQEAGADISKTVMSHLDRTILDKKELLEFAQLGCYLEYDLFGTELLHYQLGPDIDMPDDNKRIRRVRLLVEEGCEDRILVAHDIHTKTRLMKYGGHGYSHILTNVVPKMLLRGITENVLDKILIENPKQWLTFK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSLSGKVQ ------CCCCCCHHH	39.73	29759185
3	Phosphorylation	-----MSSLSGKVQT -----CCCCCCHHHH	25.84	29759185
5	Phosphorylation	---MSSLSGKVQTVL ---CCCCCCHHHHHH	38.22	29759185
7	Ubiquitination	-MSSLSGKVQTVLGL -CCCCCCHHHHHHHH	28.00	-
10	Phosphorylation	SLSGKVQTVLGLVEP CCCCHHHHHHHHCCH	22.23	20068231
18	Phosphorylation	VLGLVEPSKLGRTLT HHHHCCHHHCCCCCC	27.32	20068231
19	Acetylation	LGLVEPSKLGRTLTH HHHCCHHHCCCCCCH	66.72	25953088
19	Ubiquitination	LGLVEPSKLGRTLTH HHHCCHHHCCCCCCH	66.72	21906983
19 (in isoform 2)	Ubiquitination	-	66.72	-
48	Phosphorylation	PPCQEAISKEPIVMK CCHHHHHCCCCCEEE	37.71	-
62	Ubiquitination	KNLYWIQKNAYSHKE EEEHHHHHHCCCCHH	34.12	-
68	Ubiquitination	QKNAYSHKENLQLNQ HHHCCCCHHHCCCCH	42.21	-
81 (in isoform 2)	Ubiquitination	-	52.78	-
81	Ubiquitination	NQETEAIKEELLYFK CHHHHHHHHHHHHEE	52.78	21906983
88	Ubiquitination	KEELLYFKANGGGAL HHHHHHEECCCCCEE	27.64	21906983
111	Ubiquitination	SRDTQTLKRLAEETG CCCHHHHHHHHHHHC	49.07	21906983
141	Phosphorylation	SSETRAMSVEQLTDV CCHHHCCCHHHHHHH	22.86	-
161	Phosphorylation	LHGADGTSIKCGIIG HHCCCCCEEEECEEC	26.11	30631047
225	Ubiquitination	EAGADISKTVMSHLD HCCCCHHHHHHHHHC	45.53	21906983
226	Acetylation	AGADISKTVMSHLDR CCCCHHHHHHHHHCH	18.04	19413330
233	Methylation	TVMSHLDRTILDKKE HHHHHHCHHCCCHHH	29.99	115489575
238	Ubiquitination	LDRTILDKKELLEFA HCHHCCCHHHHHHHH	44.71	21906983
292	Methylation	VEEGCEDRILVAHDI HHCCCCCEEEEEEEC	11.22	115489559
296 (in isoform 2)	Ubiquitination	-	7.38	-
302	Ubiquitination	VAHDIHTKTRLMKYG EEEECCCCCCCHHCC	19.93	21906983
313	Phosphorylation	MKYGGHGYSHILTNV HHCCCCCHHHHHHHH	7.44	29759185
314	Phosphorylation	KYGGHGYSHILTNVV HCCCCCHHHHHHHHH	14.51	-
318	Phosphorylation	HGYSHILTNVVPKML CCHHHHHHHHHHHHH	25.93	-
327	Methylation	VVPKMLLRGITENVL HHHHHHHCCCCHHHH	30.42	115489567
330	Phosphorylation	KMLLRGITENVLDKI HHHHCCCCHHHHHHH	25.08	-
336	Ubiquitination	ITENVLDKILIENPK CCHHHHHHHHCCCCC	34.94	21906983
343	Ubiquitination	KILIENPKQWLTFK- HHHCCCCCCCCCCC-	66.73	21906983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PTER_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PTER_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PTER_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ABCE1_HUMAN	ABCE1	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.