dbPTM

PSL5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PSL5_ARATH
UniProt AC	Q9FN05
Protein Name	Probable glucan 1,3-alpha-glucosidase
Gene Name	PSL5
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	921
Subcellular Localization	Endoplasmic reticulum.
Protein Description	Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (By similarity). Essential for stable accumulation of the receptor EFR that determines the specific perception of bacterial elongation factor Tu (EF-Tu), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Required for sustained activation of EFR-mediated signaling, but not receptor FLS2-mediated signaling elicited by the bacterial flagellin flg22..
Protein Sequence	MRSLLFVLSLICFCSQTALSWKKEEFRSCDQTPFCKRARSRTPGACSLIVGDVSITDGDLVAKLLPKAPNQGDGDQIKPLILSLSVYKDGIVRLKIDEDHSLNPPKKRFQVPDVVVSEFEEKKIWLQKVATETISGDTSPSSVVYVSDGYEAVVRHDPFEVYVREKSGDRRRVVSLNSHGLFDFEQLGRKTEGDNWEEKFRTHTDSRPSGPQSISFDVSFYDSSFVYGIPEHATSFALKPTKGPGVEESEPYRLFNLDVFEYDHESPFGLYGSIPFMVSHGKSGKTSGFFWLNAAEMQIDVLANGWDAESGISLPSSHSRIDTFWMSEAGIVDTFFFVGPEPKDVVKQYASVTGTSAMPQLFATGYHQCRWNYKDEEDVAQVDSKFDEHDIPYDVLWLDIEHTDGKRYFTWDSVLFPHPEEMQKKLAAKGRKMVTIVDPHIKRDDSYFLHKEATQMGYYVKDSSGKDFDGWCWPGSSSYIDMLSPEIRKWWGGRFSYKNYVGSTPSLYTWNDMNEPSVFNGPEVTMPRDALHVGGVEHREVHNAYGYYFHMATSDGLVMREEGKDRPFVLSRAIFPGTQRYGAIWTGDNTAEWEHLRVSIPMILTLGLTGITFSGADIGGFFGNPEPELLVRWYQVGAYYPFFRGHAHHDTKRREPWLFGERNTELMRDAIHTRYTLLPYFYTLFREANVTGVPVVRPLWMEFPQDEATFSNDEAFMVGSGLLVQGVYTKGTTQASVYLPGKESWYDLRNGKTYVGGKTHKMDAPEESIPAFQKAGTIIPRKDRFRRSSSQMDNDPYTLVVALNSSQEAEGELYIDDGKSFEFRRGSYIHRRFVFSKGVLTSTNLAPPEARLSSQCLIDRIILLGHSSGPKSALVEPLNQKAEIEMGPLRMGGLVASSGTKVLTIRKPGVRVDQDWTVKIL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
571	Phosphorylation	KDRPFVLSRAIFPGT CCCCEEEEEEECCCC	19880383
689	N-linked_Glycosylation	YTLFREANVTGVPVV HHHHHHCCCCCCCEE	-
804	N-linked_Glycosylation	YTLVVALNSSQEAEG EEEEEEECCCCCEEC	-
868	Phosphorylation	IILLGHSSGPKSALV HHEECCCCCCHHHCC	19880383
898	Phosphorylation	MGGLVASSGTKVLTI CCCEEECCCCEEEEE	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PSL5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PSL5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PSL5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PSL5_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PSL5_ARATH

Related Literatures of Post-Translational Modification