dbPTM

PSD1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PSD1_SCHPO
UniProt AC	O14333
Protein Name	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03208, ECO:0000303\|PubMed:19286980}
Gene Name	psd1 {ECO:0000255\|HAMAP-Rule:MF_03208, ECO:0000303\|PubMed:19286980}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	437
Subcellular Localization	Phosphatidylserine decarboxylase 1 beta chain: Mitochondrion . Mitochondrion inner membrane Single-pass membrane protein Intermembrane side . Phosphatidylserine decarboxylase 1 alpha chain: Mitochondrion . Mitochondrion inner membrane Peripheral me
Protein Description	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity). Together with psd2 and psd3, responsible for the majority of phosphatidylethanolamine synthesis. [PubMed: 19286980]
Protein Sequence	MLKFHRNVKPQFGAFARYSSLGKHNSRKRVGIIRLAYGLTGIGLVGLAGFAWAQDRHEKTYQKKGVQVEGPWQFYVLTTLPLRTLSRWWGYVNRIEIPLWMRVPAFGLYSKIFGCNLTEADPDDVRQYKNLAEFFTRKLKPGARVIDPDAPIVIPADGKILNYGVIEGGQLEQVKGITYSLDALLGDEKLARLKRSHAIPSPDHIPHIRQEEFAKLNGIHYSLQDLMGHDHGERPSHVKDASAQHIDLLSSTKVAAKSQFTLFGSRETNCLYYAVIYLAPGDYHRFHSPTDWVVERRRHFSGELFSVSPFMARRLGNLFILNERVALMGRYKYGFMSMIPVGATNVGSIRIKFDKDLCTNQFGKLGPVGTFDEAVYTSSSSILHGHPLLRGDEVGNFELGSTVVLVFEAPADFEFLVKQGQKVRVGLPLGRVVPSSH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
401	Pyruvic acid (Ser)	VGNFELGSTVVLVFE ECCEECCCEEEEEEE	30.56	-
401	Pyruvate	VGNFELGSTVVLVFE ECCEECCCEEEEEEE	30.56	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PSD1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PSD1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PSD1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PSD1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PSD1_SCHPO

Related Literatures of Post-Translational Modification