PSB10_MOUSE - dbPTM
PSB10_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PSB10_MOUSE
UniProt AC O35955
Protein Name Proteasome subunit beta type-10
Gene Name Psmb10
Organism Mus musculus (Mouse).
Sequence Length 273
Subcellular Localization Cytoplasm . Nucleus.
Protein Description The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Plays a role in determining the T-cell repertoire for an antiviral T-cell response..
Protein Sequence MLKQAVEPTGGFSFENCQRNASLEHVLPGLRVPHARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVITAGGAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETVQAMEVE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MLKQAVEP
-------CCCCCCCC
10.74-
22PhosphorylationENCQRNASLEHVLPG
CHHCCCCCHHHHCCC
37.5327180971
229PhosphorylationAKLQRALSTPTEPVQ
HHHHHHHCCCCCCCH
31.2126824392
230PhosphorylationKLQRALSTPTEPVQR
HHHHHHCCCCCCCHH
34.7730635358
232PhosphorylationQRALSTPTEPVQRAG
HHHHCCCCCCCHHHC
53.6728833060
248PhosphorylationYRFAPGTTPVLTREV
CCCCCCCCCCCCCCC
19.8129514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PSB10_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PSB10_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PSB10_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PSB10_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PSB10_MOUSE

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Related Literatures of Post-Translational Modification

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