UniProt ID | PSB10_MOUSE | |
---|---|---|
UniProt AC | O35955 | |
Protein Name | Proteasome subunit beta type-10 | |
Gene Name | Psmb10 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 273 | |
Subcellular Localization | Cytoplasm . Nucleus. | |
Protein Description | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Plays a role in determining the T-cell repertoire for an antiviral T-cell response.. | |
Protein Sequence | MLKQAVEPTGGFSFENCQRNASLEHVLPGLRVPHARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVITAGGAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETVQAMEVE | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
1 | Acetylation | -------MLKQAVEP -------CCCCCCCC | 10.74 | - | |
22 | Phosphorylation | ENCQRNASLEHVLPG CHHCCCCCHHHHCCC | 37.53 | 27180971 | |
229 | Phosphorylation | AKLQRALSTPTEPVQ HHHHHHHCCCCCCCH | 31.21 | 26824392 | |
230 | Phosphorylation | KLQRALSTPTEPVQR HHHHHHCCCCCCCHH | 34.77 | 30635358 | |
232 | Phosphorylation | QRALSTPTEPVQRAG HHHHCCCCCCCHHHC | 53.67 | 28833060 | |
248 | Phosphorylation | YRFAPGTTPVLTREV CCCCCCCCCCCCCCC | 19.81 | 29514104 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PSB10_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PSB10_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PSB10_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of PSB10_MOUSE !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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