PSA72_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSA72_DROME
• UniProt AC: Q24178
• Protein Name: Proteasome subunit alpha type-7-1A
• Gene Name: Prosalpha4T1
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 249
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity..
• Protein Sequence: MSSRYGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKISMLDRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVTTKCDAIKLAMRALLEVTQMSQMRLEVAVLENGKPMKMLDSVVISEIVKIVQNEKELQAKAHKMKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	QEAVRKGSTAVGVRG HHHHHCCCCEEECCC	19.07	19429919
33	Phosphorylation	EAVRKGSTAVGVRGA HHHHCCCCEEECCCC	33.75	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSA72_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSA72_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSA72_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of PSA72_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.